DACT1 and APPL1

  • Data Source:
  • BioGRID (two hybrid)

DACT1

APPL1

Description dishevelled binding antagonist of beta catenin 1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Brain morphology (MOSTest) ( 32665545)
  • Colorectal cancer or advanced adenoma ( 30510241)
  • Dentate gyrus granule cell layer volume (corrected for total hippocampal volume) ( 30279459)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Hippocampal subfield CA1 volume (corrected for total hippocampal volume) ( 30279459)
  • Hippocampal tail volume (corrected for total hippocampal volume) ( 30279459)
  • Metabolite levels ( 23823483)
  • Occipital lobe volume ( 31396565)
  • Parietal lobe volume ( 31396565)
Interacting Genes 6 interacting genes: APPL1 C7orf25 CSNK2B PPP1CC SH3GL2 TK1 64 interacting genes: ADI1 ADIPOR1 ADIPOR2 AGL AKT1 AKT2 ANKRD1 APPL2 ATP2A1 BATF3 BIN1 BRWD1 C1QTNF9 CBL CBLB CIPC CMTM4 CTTNBP2 DACT1 DCC DNM2 DOK2 DOK3 DOK7 DPYSL5 DTNA DYSF EGFR FARS2 FSHR GPC3 HDAC2 HSPB1 ID1 INO80E KLF15 KXD1 LUC7L MAGEA9 MAGEC3 MAP3K1 MEOX1 MTA2 MYCBP2 MYH3 PIK3CA PIK3R1 PIK3R2 PLEKHF2 PNMA5 RAB21 RAB5A RBBP7 RHEBL1 RUVBL2 SCAPER SH2D2A SOCS6 SPART TP53 TP53BP2 TRAF2 UBE2O ZNF829
Entrez ID 51339 26060
HPRD ID 09709 05053
Ensembl ID ENSG00000165617 ENSG00000157500
Uniprot IDs Q9NYF0 Q9UKG1
PDB IDs 2EJ8 2ELA 2ELB 2Q12 2Q13 2Z0N 2Z0O 5C5B
Enriched GO Terms of Interacting Partners?
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