CRBN and EGR1

CRBN

EGR1

Description cereblon early growth response 1
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis (C9orf72 mutation interaction) ( 22959728)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321)
  • Schizophrenia ( 28991256 25056061)
Interacting Genes 36 interacting genes: APPL2 BCL6 BCL6B BSG CSNK1A1 CYP19A1 EGR1 EGR4 GLUL GRB2 GSPT1 GZF1 HIC1 HIC2 IKZF3 KDM1A KPNB1 MISP OSR1 OSR2 PAK5 PIK3R3 RBPMS RBX1 SALL1 SALL3 SALL4 SLC16A1 SQSTM1 SUV39H1 TP53 UBE2D1 WIZ ZBTB7A ZBTB7B ZFP91 23 interacting genes: CDKN2A CEBPB CRBN CREBBP CSNK2A1 DNMT3L EP300 ERBB3 IL1B JUN MTDH NAB1 NAB2 NFATC1 NFATC2 PITX1 PSMA3 RELA SP1 SRA1 SREBF2 TP53 WT1
Entrez ID 51185 1958
HPRD ID 16750 00549
Ensembl ID ENSG00000113851 ENSG00000120738
Uniprot IDs Q96SW2 P18146 Q546S1
PDB IDs 4M91 4TZ4 5FQD 5HXB 5V3O 6BN7 6BN8 6BN9 6BNB 6BOY 6H0F 6H0G 6UML 7BQU 7BQV 4R2A 4R2C 4R2D 4X9J 5N14
Enriched GO Terms of Interacting Partners?
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