PLIN2 and ABHD5

Data Source:
HPRD (two hybrid, in vitro)

		PLIN2	ABHD5
Description		perilipin 2	abhydrolase domain containing 5, lysophosphatidic acid acyltransferase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Endoplasmic Reticulum Lipid Droplet Cytosol Plasma Membrane	Nucleoplasm Mitochondrion Lipid Droplet Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	1-acylglycerol-3-phosphate O-acyltransferase Activity Triglyceride Lipase Activity Protein Binding Lysophosphatidic Acid Acyltransferase Activity Carboxylic Ester Hydrolase Activity
	Biological Process	Positive Regulation Of Sequestering Of Triglyceride Response To Organic Cyclic Compound Long-chain Fatty Acid Transport Regulation Of Lipid Metabolic Process Lipid Storage Response To Drug	Fatty Acid Metabolic Process Phosphatidic Acid Biosynthetic Process Negative Regulation Of Sequestering Of Triglyceride Positive Regulation Of Triglyceride Catabolic Process Cell Differentiation Positive Regulation Of Lipoprotein Lipase Activity Lipid Homeostasis
Pathways		PPARA activates gene expression Lipophagy Chaperone Mediated Autophagy Late endosomal microautophagy	Triglyceride catabolism
Drugs
Diseases			Dorfman-Chanarin syndrome; Chanarin-Dorfman syndrome
GWAS		Abdominal aortic calcification levels ( 31659325) Systolic blood pressure ( 30578418)	General risk tolerance (MTAG) ( 30643258) Inflammatory skin disease ( 25574825)
Interacting Genes		7 interacting genes: ABHD5 ARF1 DESI2 HTATIP2 MAPK10 POGZ SFT2D2	21 interacting genes: CERCAM COQ8A DGAT2L6 GAD2 GET1 GRIA4 MIEF1 PCNX2 PLIN1 PLIN2 PLIN3 PNPLA2 RBFA RNF24 RUSC1 SH3GLB1 SLC44A3 TMEM14B TMEM31 TPD52L2 ZCCHC12
Entrez ID		123	51099
HPRD ID		00057	11986
Ensembl ID		ENSG00000147872	ENSG00000011198
Uniprot IDs		Q6FHZ7 Q99541	A0A0S2Z5D6 Q8WTS1
PDB IDs
Enriched GO Terms of Interacting Partners?
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