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PAX5 and GRHL2
Data Source:
BioGRID
(two hybrid)
PAX5
GRHL2
Description
paired box 5
grainyhead like transcription factor 2
Image
GO Annotations
Cellular Component
Chromatin
Fibrillar Center
Nucleoplasm
Cytosol
Intracellular Membrane-bounded Organelle
Chromatin
Nucleus
Nucleoplasm
Cell-cell Junction
Membrane
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Intronic Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Chromatin DNA Binding
Sequence-specific DNA Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Humoral Immune Response
Multicellular Organism Development
Spermatogenesis
Aging
Animal Organ Morphogenesis
Lateral Ventricle Development
Cerebral Cortex Development
Adult Behavior
Skeletal Muscle Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Embryonic Cranial Skeleton Morphogenesis
Anatomical Structure Development
Regulation Of B Cell Receptor Signaling Pathway
Negative Regulation Of Histone H3-K9 Methylation
Neural Tube Closure
Cardiac Ventricle Morphogenesis
Epithelial Cell Morphogenesis
Regulation Of Transcription By RNA Polymerase II
Cell Adhesion
Brain Development
Cell Population Proliferation
Epidermis Development
Neural Tube Development
Cell Junction Assembly
Multicellular Organism Growth
Embryonic Digit Morphogenesis
Camera-type Eye Development
Regulation Of DNA Methylation
Negative Regulation Of Keratinocyte Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Embryonic Cranial Skeleton Morphogenesis
Positive Regulation Of Telomerase Activity
Face Development
Lung Lobe Morphogenesis
Lung Epithelial Cell Differentiation
Epithelial Cell Morphogenesis Involved In Placental Branching
Anterior Neural Tube Closure
Bicellular Tight Junction Assembly
Epithelium Migration
Pathways
RUNX1 regulates transcription of genes involved in BCR signaling
Drugs
Diseases
Lymphoplasmacytic lymphoma
GWAS
Adult body size (
32376654
)
Alzheimer's disease (
30636644
)
Composite immunoglobulin trait (IgA/IgM) (
28628107
)
Coronary artery disease in type 1 diabetes (
29695241
)
HIV-1 susceptibility (
25786224
)
Intelligence (
22449649
)
Major depressive disorder (
27479909
)
Moderate to vigorous physical activity levels (
29899525
)
Morning person (
30696823
)
Obesity-related traits (
22013104
)
Bronchopulmonary dysplasia (
23897914
)
Rheumatoid arthritis (
30423114
24390342
)
Interacting Genes
55 interacting genes:
ACOT12
BCAS2
C1orf109
CCNC
CDK3
CIB3
CKS1B
CREBBP
CSNK2A1
CXorf38
DAXX
DTX2
EBF1
EP300
ETS1
FBLN1
GNG13
GRHL2
HGS
HMBOX1
HMGB3
HOXC8
ID2
ID3
KLHL38
KPNA1
KPNA2
KRTAP10-8
KRTAP9-3
LARP4
LDLRAP1
LONRF1
MAPK1
MAPK9
MYB
NEIL2
NFYC
NGLY1
OSGIN1
PNMA5
RAD52
RB1
RNF144B
RUNX1
SAE1
SEC14L4
STAC
TBP
TLE4
TLK2
UBE2I
UBE3A
UBXN2B
UBXN7
ZMYM5
6 interacting genes:
APP
GRHL3
LMO4
PAX5
PAX6
PIAS2
Entrez ID
5079
79977
HPRD ID
01334
10545
Ensembl ID
ENSG00000196092
ENSG00000083307
Uniprot IDs
C0KTE5
C0KTF5
E7EQT0
E7ERK2
E7ERW5
E7ES87
Q02548
B4DL28
Q6ISB3
PDB IDs
1K78
1MDM
5MR7
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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