CNOT4 and CNOT3

Data Source:
BioGRID (pull down)

		CNOT4	CNOT3
Description		CCR4-NOT transcription complex subunit 4	CCR4-NOT transcription complex subunit 3
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GO Annotations	Cellular Component	Nucleus Cytosol CCR4-NOT Complex	P-body Nucleus Cytosol CCR4-NOT Complex CCR4-NOT Core Complex
	Molecular Function	RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Nuclear-transcribed MRNA Poly(A) Tail Shortening Ubiquitin-dependent Protein Catabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Protein Ubiquitination Regulation Of Megakaryocyte Differentiation Protein Autoubiquitination	Nuclear-transcribed MRNA Poly(A) Tail Shortening Trophectodermal Cell Differentiation Regulation Of Transcription, DNA-templated Regulation Of Translation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Gene Silencing By RNA Positive Regulation Of Cold-induced Thermogenesis Regulation Of Stem Cell Population Maintenance
Pathways		Deadenylation of mRNA TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	Deadenylation of mRNA TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Heel bone mineral density ( 30598549) Household income (MTAG) ( 31844048) Meat-related diet ( 32066663) Numerical cognitive ability ( 31620175)	PEG-asparaginase hypersensitivity without enzyme activity in childhood acute lymphoblastic leukaemia ( 30450575)
Interacting Genes		18 interacting genes: CNOT1 CNOT2 CNOT3 CNOT6 CNOT8 EP300 IL36RN KDM5C RBM15 UBE2B UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2N UBE2W	8 interacting genes: CAND1 CAND2 CNOT1 CNOT2 CNOT4 CNOT8 CREBBP ID3
Entrez ID		4850	4849
HPRD ID		05369	05368
Ensembl ID		ENSG00000080802	ENSG00000088038
Uniprot IDs		A0A024R776 A0A024R781 A0A024R785 O95628	A0A024R4R3 O75175
PDB IDs		1E4U 1UR6	4C0D 4C0G 5FU6 5FU7
Enriched GO Terms of Interacting Partners?
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