CNOT3 and CNOT4

Data Source:
BioGRID (pull down)

		CNOT3	CNOT4
Description		CCR4-NOT transcription complex subunit 3	CCR4-NOT transcription complex subunit 4
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GO Annotations	Cellular Component	P-body Nucleus Cytosol CCR4-NOT Complex CCR4-NOT Core Complex	Nucleus Cytosol CCR4-NOT Complex
	Molecular Function	Protein Binding	RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding
	Biological Process	Nuclear-transcribed MRNA Poly(A) Tail Shortening Trophectodermal Cell Differentiation Regulation Of Transcription, DNA-templated Regulation Of Translation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Gene Silencing By RNA Positive Regulation Of Cold-induced Thermogenesis Regulation Of Stem Cell Population Maintenance	Nuclear-transcribed MRNA Poly(A) Tail Shortening Ubiquitin-dependent Protein Catabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Protein Ubiquitination Regulation Of Megakaryocyte Differentiation Protein Autoubiquitination
Pathways		Deadenylation of mRNA TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	Deadenylation of mRNA TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
Drugs
Diseases
GWAS		PEG-asparaginase hypersensitivity without enzyme activity in childhood acute lymphoblastic leukaemia ( 30450575)	Appendicular lean mass ( 33097823) Heel bone mineral density ( 30598549) Household income (MTAG) ( 31844048) Meat-related diet ( 32066663) Numerical cognitive ability ( 31620175)
Interacting Genes		8 interacting genes: CAND1 CAND2 CNOT1 CNOT2 CNOT4 CNOT8 CREBBP ID3	18 interacting genes: CNOT1 CNOT2 CNOT3 CNOT6 CNOT8 EP300 IL36RN KDM5C RBM15 UBE2B UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2N UBE2W
Entrez ID		4849	4850
HPRD ID		05368	05369
Ensembl ID		ENSG00000088038	ENSG00000080802
Uniprot IDs		A0A024R4R3 O75175	A0A024R776 A0A024R781 A0A024R785 O95628
PDB IDs		4C0D 4C0G 5FU6 5FU7	1E4U 1UR6
Enriched GO Terms of Interacting Partners?
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