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NCL and RAD51
Data Source:
BioGRID
(pull down)
NCL
RAD51
Description
nucleolin
RAD51 recombinase
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Spliceosomal Complex
Chromosome
Nucleolus
Cell Cortex
Membrane
Cytoplasmic Ribonucleoprotein Granule
Extracellular Exosome
Ribonucleoprotein Complex
Nuclear Chromosome
Chromosome, Telomeric Region
Chromatin
Condensed Chromosome
Condensed Nuclear Chromosome
Lateral Element
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Mitochondrial Matrix
Microtubule Organizing Center
PML Body
Protein-containing Complex
Site Of Double-strand Break
Perinuclear Region Of Cytoplasm
Molecular Function
RNA Binding
Protein Binding
Protein C-terminus Binding
Telomeric DNA Binding
Identical Protein Binding
DNA Topoisomerase Binding
MRNA 5'-UTR Binding
Recombinase Activity
Chromatin Binding
Double-stranded DNA Binding
Single-stranded DNA Binding
Protein Binding
ATP Binding
Protein C-terminus Binding
DNA-dependent ATPase Activity
Single-stranded DNA Helicase Activity
Enzyme Binding
Identical Protein Binding
DNA Polymerase Binding
Biological Process
Angiogenesis
Negative Regulation Of Translation
Positive Regulation Of MRNA Splicing, Via Spliceosome
Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I
Telomere Maintenance Via Recombination
Double-strand Break Repair Via Homologous Recombination
DNA Recombinase Assembly
Regulation Of Protein Phosphorylation
DNA Unwinding Involved In DNA Replication
DNA Repair
DNA Recombination
Mitotic Recombination
Cellular Response To DNA Damage Stimulus
Reciprocal Meiotic Recombination
Response To Toxic Substance
Response To X-ray
Regulation Of Double-strand Break Repair Via Homologous Recombination
Telomere Maintenance Via Telomere Lengthening
Replication Fork Processing
Interstrand Cross-link Repair
Strand Invasion
Response To Drug
Positive Regulation Of DNA Ligation
Meiotic Cell Cycle
Chromosome Organization Involved In Meiotic Cell Cycle
Negative Regulation Of G0 To G1 Transition
Cellular Response To Ionizing Radiation
Cellular Response To Gamma Radiation
Cellular Response To Hydroxyurea
Cellular Response To Cisplatin
Cellular Response To Camptothecin
Response To Glucoside
Replication-born Double-strand Break Repair Via Sister Chromatid Exchange
Mitotic Recombination-dependent Replication Fork Processing
Pathways
Major pathway of rRNA processing in the nucleolus and cytosol
HDR through Single Strand Annealing (SSA)
HDR through Homologous Recombination (HRR)
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
Resolution of D-loop Structures through Holliday Junction Intermediates
Homologous DNA Pairing and Strand Exchange
Presynaptic phase of homologous DNA pairing and strand exchange
Transcriptional Regulation by E2F6
Meiotic recombination
Drugs
Phosphoaminophosphonic Acid-Adenylate Ester
Amuvatinib
Diseases
GWAS
Attention deficit hyperactivity disorder (
23728934
)
Common carotid intima-media thickness in HIV negative individuals (
29206233
)
Eating disorders (purging via substances) (
23568457
)
Height (
31562340
)
Noise-induced hearing loss (
26121033
)
Anxiety and stress-related disorders (
31116379
)
Malaria (
31844061
)
Mean spheric corpuscular volume (
32888494
)
Refractive error (
32231278
)
Interacting Genes
57 interacting genes:
ADAP1
ADAP2
CD3E
CDK1
CDKN2A
CLK1
CSNK2A1
CSNK2A2
DUX4
ERG
ESR1
ETS1
FMR1
GRB2
GZF1
GZMA
H1-2
H2AC20
H2AX
H2BC21
H3-4
HMGA1
IL7R
LINC01554
MDC1
MDK
MDM2
MYB
MYBL1
NBN
NDRG1
NPM1
NR3C1
PARP1
POLR1G
PPARGC1A
PPM1D
PRKCZ
PRMT5
PTGS1
RAD51
S100A11
SREK1
SRPK2
SSB
STAU1
SUMO2
TERF2
TERT
TOP1
TP53
VHL
XRCC6
YWHAQ
ZFP36
ZFP41
ZNF689
94 interacting genes:
-
ABL1
AGO2
ATM
ATRX
BARD1
BCCIP
BCR
BLM
BRCA1
BRCA2
C1orf112
CASP3
CASP7
CCND1
CDH13
CHD3
CHEK1
CSNK2A1
CSNK2B
CST6
CTCF
DDB2
DMC1
DNAJA3
ENAH
EP400
ERCC2
ERCC5
EVL
FANCD2
FANCI
FBH1
FIGNL1
HID1
HNRNPC
HSP90AA1
IL24
IRS1
ITIH5
MAPK8IP3
MDC1
MMS22L
MND1
MSH4
NBN
NCL
NELFB
NXF1
PALB2
PARPBP
PCSK1N
PDS5B
PFN1
PLK1
POLA1
RAD18
RAD51AP1
RAD51AP2
RAD51B
RAD51C
RAD52
RAD54B
RAD54L
RECQL5
RELA
RFWD3
RPA1
RPA2
RPA3
SEM1
SFR1
SIRT2
ST14
SUMO1
SUMO2
SWSAP1
TFF1
TP53
TP53BP1
UBE2I
UCHL3
UGDH
UHRF2
UMPS
USP10
VASP
VIM
WDR48
WRN
XPO1
XRCC2
XRCC3
ZDHHC17
Entrez ID
4691
5888
HPRD ID
01245
01557
Ensembl ID
ENSG00000115053
ENSG00000051180
Uniprot IDs
B3KM80
P19338
Q06609
PDB IDs
2FC8
2FC9
2KRR
1B22
1N0W
5H1B
5H1C
5JZC
5NP7
5NWL
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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