NASP and H3-5

Data Source:
BioGRID (two hybrid, two hybrid)

		NASP	H3-5
Description		nuclear autoantigenic sperm protein	H3.5 histone
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Protein-containing Complex	Nucleosome Euchromatin Nucleus
	Molecular Function	Protein Binding Histone Binding	Protein Binding Nucleosomal DNA Binding Protein Heterodimerization Activity
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Blastocyst Development DNA Replication DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Male Gonad Development Protein Transport Response To Testosterone CENP-A Containing Nucleosome Assembly Histone Exchange	Positive Regulation Of Cell Growth
Pathways
Drugs
Diseases
GWAS		Blood metabolite levels ( 24816252) Blood protein levels ( 28240269) Body mass index ( 26426971) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Hematocrit ( 27863252) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		26 interacting genes: ASF1A CDC42 H1-1 H1-2 H3-4 H3-5 H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 HDAC6 LUC7L2 MTNR1A PTK2 TERF2 TERF2IP ULK2	15 interacting genes: DAXX DNAJC9 FBLIM1 KAT6A KDM1A KDM4B NASP NSD3 PRMT5 PRMT6 PRMT7 SETMAR SMYD1 SMYD3 SUV39H1
Entrez ID		4678	440093
HPRD ID		04423	18443
Ensembl ID		ENSG00000132780	ENSG00000188375
Uniprot IDs		P49321 Q5T626	Q6NXT2
PDB IDs			2PUY 3KV4 4Z5T 5BWN 5BWO 5F6K 5I3L 6OI3
Enriched GO Terms of Interacting Partners?
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