NASP and H1-2

Data Source:
HPRD (in vitro)

		NASP	H1-2
Description		nuclear autoantigenic sperm protein	H1.2 linker histone, cluster member
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Protein-containing Complex	Nucleosome Euchromatin Nucleus
	Molecular Function	Protein Binding Histone Binding	Double-stranded DNA Binding RNA Binding Protein Binding Chromatin DNA Binding Nucleosomal DNA Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Blastocyst Development DNA Replication DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Male Gonad Development Protein Transport Response To Testosterone CENP-A Containing Nucleosome Assembly Histone Exchange	Nucleosome Assembly Nucleosome Positioning Chromosome Condensation Negative Regulation Of Chromatin Silencing Negative Regulation Of DNA Recombination
Pathways			Apoptosis induced DNA fragmentation Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS		Blood metabolite levels ( 24816252) Blood protein levels ( 28240269) Body mass index ( 26426971) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Hematocrit ( 27863252) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		26 interacting genes: ASF1A CDC42 H1-1 H1-2 H3-4 H3-5 H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 HDAC6 LUC7L2 MTNR1A PTK2 TERF2 TERF2IP ULK2	30 interacting genes: AEBP2 APP ASXL1 CDC73 CSNK2A2 CTNNB1 CTR9 CUL4A DDB1 F10 IL7R IRAK4 KPNA7 KPNB1 LEO1 NASP NCL NSD1 PAF1 PARP1 POLR2A PRKCA PRKDC PUF60 RBM39 SNCA VHL WDR12 WDR5 YBX1
Entrez ID		4678	3006
HPRD ID		04423	07514
Ensembl ID		ENSG00000132780	ENSG00000187837
Uniprot IDs		P49321 Q5T626	P16403
PDB IDs
Enriched GO Terms of Interacting Partners?
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