MMP14 and TIMP2

  • Data Source:
  • BioGRID (pull down, pull down)
  • HPRD (in vivo, in vitro)

MMP14

TIMP2

Description matrix metallopeptidase 14 TIMP metallopeptidase inhibitor 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cardiovascular death, myocardial infarction or stroke in response to clopidogrel treatment ( 32472697)
  • Diastolic blood pressure ( 30224653)
  • Dupuytren's disease ( 28886342)
  • Heel bone mineral density ( 30598549 28869591)
  • Prostate cancer ( 29892016)
  • Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes 35 interacting genes: ACAN ADI1 AQP6 BCAR1 C1QBP CAV1 CCL7 CLDN1 EBP ELOVL4 F11R F12 FHL3 FURIN HSD17B13 ITGAV KASH5 KISS1 LRP1 LUM MMP13 MMP2 MMP3 MSMO1 PLLP RRAD SDC1 SPOCK1 SPOCK3 STOM TIMP2 TIMP3 TIMP4 TMEM31 ZUP1 6 interacting genes: ITGA3 ITGB1 MMP14 MMP2 MMP8 UBQLN2
Entrez ID 4323 7077
HPRD ID 02856 01784
Ensembl ID ENSG00000157227 ENSG00000035862
Uniprot IDs P50281 A0A140VK57 P16035
PDB IDs 1BQQ 1BUV 2MQS 3C7X 3MA2 3X23 4P3C 4P3D 4QXU 5H0U 6CLZ 6CM1 1BR9 1GXD 2TMP 4ILW
Enriched GO Terms of Interacting Partners?
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