MMP14 and ACAN

  • Data Source:
  • HPRD (in vitro, in vivo)

MMP14

ACAN

Description matrix metallopeptidase 14 aggrecan
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cardiovascular death, myocardial infarction or stroke in response to clopidogrel treatment ( 32472697)
  • Diastolic blood pressure ( 30224653)
  • Dupuytren's disease ( 28886342)
  • Heel bone mineral density ( 30598549 28869591)
  • Prostate cancer ( 29892016)
  • Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes 35 interacting genes: ACAN ADI1 AQP6 BCAR1 C1QBP CAV1 CCL7 CLDN1 EBP ELOVL4 F11R F12 FHL3 FURIN HSD17B13 ITGAV KASH5 KISS1 LRP1 LUM MMP13 MMP2 MMP3 MSMO1 PLLP RRAD SDC1 SPOCK1 SPOCK3 STOM TIMP2 TIMP3 TIMP4 TMEM31 ZUP1 18 interacting genes: ADAMTS1 ADAMTS4 ADAMTS5 CTSB FBLN1 FBLN2 HAPLN1 LUM MMP1 MMP14 MMP19 MMP2 MMP20 MMP3 MMP8 PTPRF TNFAIP6 TNR
Entrez ID 4323 176
HPRD ID 02856 01123
Ensembl ID ENSG00000157227 ENSG00000157766
Uniprot IDs P50281 P16112
PDB IDs 1BQQ 1BUV 2MQS 3C7X 3MA2 3X23 4P3C 4P3D 4QXU 5H0U 6CLZ 6CM1 4MD4
Enriched GO Terms of Interacting Partners?
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