MMP14 and MMP3

  • Data Source:
  • BioGRID (enzymatic study)

MMP14

MMP3

Description matrix metallopeptidase 14 matrix metallopeptidase 3
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cardiovascular death, myocardial infarction or stroke in response to clopidogrel treatment ( 32472697)
  • Diastolic blood pressure ( 30224653)
  • Dupuytren's disease ( 28886342)
  • Heel bone mineral density ( 30598549 28869591)
  • Prostate cancer ( 29892016)
  • Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
  • Alzheimer's disease ( 22832961)
  • Blood protein levels ( 30072576 28240269)
  • Blood protein levels in cardiovascular risk ( 28369058)
  • Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798)
  • Peripheral artery disease ( 31285632)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
Interacting Genes 35 interacting genes: ACAN ADI1 AQP6 BCAR1 C1QBP CAV1 CCL7 CLDN1 EBP ELOVL4 F11R F12 FHL3 FURIN HSD17B13 ITGAV KASH5 KISS1 LRP1 LUM MMP13 MMP2 MMP3 MSMO1 PLLP RRAD SDC1 SPOCK1 SPOCK3 STOM TIMP2 TIMP3 TIMP4 TMEM31 ZUP1 19 interacting genes: ACAN BCAN CCL13 CCL2 CCL7 CCL8 DCN HAPLN1 IGFBP3 MEOX2 MMP14 PLG SERPINE1 SPOCK1 SPOCK3 SPP1 TIMP1 TIMP3 TNFSF11
Entrez ID 4323 4314
HPRD ID 02856 01703
Ensembl ID ENSG00000157227 ENSG00000149968
Uniprot IDs P50281 P08254
PDB IDs 1BQQ 1BUV 2MQS 3C7X 3MA2 3X23 4P3C 4P3D 4QXU 5H0U 6CLZ 6CM1 1B3D 1B8Y 1BIW 1BM6 1BQO 1C3I 1C8T 1CAQ 1CIZ 1CQR 1D5J 1D7X 1D8F 1D8M 1G05 1G49 1G4K 1HFS 1HY7 1M1W 1OO9 1QIA 1QIC 1SLM 1SLN 1UEA 1UMS 1UMT 1USN 2D1O 2JNP 2JT5 2JT6 2SRT 2USN 3OHL 3OHO 3USN 4DPE 4G9L 4JA1 6MAV 6N9D
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?