MIP and SLC14A1

Data Source:
BioGRID (two hybrid)

		MIP	SLC14A1
Description		major intrinsic protein of lens fiber	solute carrier family 14 member 1 (Kidd blood group)
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Gap Junction Integral Component Of Membrane Apical Plasma Membrane	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane
	Molecular Function	Structural Constituent Of Eye Lens Protein Binding Calmodulin Binding Water Channel Activity	Water Transmembrane Transporter Activity Urea Channel Activity
	Biological Process	Lens Development In Camera-type Eye Water Transport Visual Perception Positive Regulation Of Cell Adhesion Response To Stimulus Protein Homotetramerization Transmembrane Transport Gap Junction-mediated Intercellular Transport	Water Transport Urea Transport Transmembrane Transport Urea Transmembrane Transport
Pathways		Passive transport by Aquaporins	Transport of bile salts and organic acids, metal ions and amine compounds
Drugs		B-nonylglucoside
Diseases
GWAS		Axial length ( 24144296)	Bladder cancer ( 21750109 21824976) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin concentration ( 29403010) Pursuit maintenance gain ( 29064472) Sum of carotid plaque area ( 32469969) Sum of stenosis ( 32469969)
Interacting Genes		47 interacting genes: AQP9 ATP6V0B CALM1 CD40 CISD2 CLDN5 CRYAA CRYAB CRYBB2 CRYGC ERGIC3 ERVFRD-1 FAM209A FCGR2A FOXA2 GJA3 GJA8 GJB5 GOLM1 GPX8 KCNJ6 LHFPL5 LMNA LRRC4C MFF MGST3 MRM3 MRPS18B MUC1 PDZK1IP1 PRKACA RELL2 SAR1A SGPL1 SLC14A1 SLC18A1 SSMEM1 STX1A STX2 SYAP1 SYT1 SYT2 TMEM139 TMEM154 TMEM52B TMX2 ZFPL1	11 interacting genes: BTN2A2 C1GALT1 FIS1 GIMAP1 MIP RTP2 SNORC STRIT1 THSD7B TMEM97 TMIE
Entrez ID		4284	6563
HPRD ID		01098	00195
Ensembl ID		ENSG00000135517	ENSG00000141469
Uniprot IDs		P30301	B4DFJ8 B4DHU3 F5GWS2 G0W2N5 Q13336
PDB IDs			6QD5
Enriched GO Terms of Interacting Partners?
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