SLC14A1 and FIS1

Data Source:
BioGRID (two hybrid)

		SLC14A1	FIS1
Description		solute carrier family 14 member 1 (Kidd blood group)	fission, mitochondrial 1
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane	Mitochondrion Peroxisome Integral Component Of Peroxisomal Membrane Endoplasmic Reticulum Membrane Integral Component Of Mitochondrial Outer Membrane Protein-containing Complex
	Molecular Function	Water Transmembrane Transporter Activity Urea Channel Activity	Protein Binding Identical Protein Binding
	Biological Process	Water Transport Urea Transport Transmembrane Transport Urea Transmembrane Transport	Mitochondrial Fission Autophagy Of Mitochondrion Release Of Cytochrome C From Mitochondria Protein Targeting To Mitochondrion Positive Regulation Of Cytosolic Calcium Ion Concentration Mitochondrial Fusion Regulation Of Mitochondrion Organization Peroxisome Fission Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Calcium-mediated Signaling Using Intracellular Calcium Source Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Mitochondrial Fragmentation Involved In Apoptotic Process Positive Regulation Of Mitochondrial Calcium Ion Concentration Mitochondrion Morphogenesis Positive Regulation Of Mitochondrial Fission Positive Regulation Of Protein Targeting To Membrane Negative Regulation Of ATP Metabolic Process Negative Regulation Of Fatty Acid Transport Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Transport of bile salts and organic acids, metal ions and amine compounds	Class I peroxisomal membrane protein import
Drugs
Diseases
GWAS		Bladder cancer ( 21750109 21824976) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin concentration ( 29403010) Pursuit maintenance gain ( 29064472) Sum of carotid plaque area ( 32469969) Sum of stenosis ( 32469969)	Rheumatoid arthritis ( 30891314)
Interacting Genes		11 interacting genes: BTN2A2 C1GALT1 FIS1 GIMAP1 MIP RTP2 SNORC STRIT1 THSD7B TMEM97 TMIE	30 interacting genes: A2M ABHD6 APH1A BCAP31 CREB3 DNM1L EBP ERGIC3 FAM209A FAM210B FFAR2 JAGN1 KASH5 KCNJ6 MARCHF5 MMGT1 NOS3 PIGP RNASEK SCN3B SLC10A6 SLC14A1 SLC22A1 SLC22A2 SPCS1 TBC1D15 TMEM14B TMPPE UBC VKORC1
Entrez ID		6563	51024
HPRD ID		00195	12352
Ensembl ID		ENSG00000141469	ENSG00000214253
Uniprot IDs		B4DFJ8 B4DHU3 F5GWS2 G0W2N5 Q13336	Q9Y3D6
PDB IDs		6QD5	1NZN 1PC2
Enriched GO Terms of Interacting Partners?
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