MIP and GJA3

Data Source:
HPRD (in vivo)

		MIP	GJA3
Description		major intrinsic protein of lens fiber	gap junction protein alpha 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Gap Junction Integral Component Of Membrane Apical Plasma Membrane	Integral Component Of Plasma Membrane Connexin Complex
	Molecular Function	Structural Constituent Of Eye Lens Protein Binding Calmodulin Binding Water Channel Activity	Gap Junction Channel Activity Gap Junction Hemi-channel Activity
	Biological Process	Lens Development In Camera-type Eye Water Transport Visual Perception Positive Regulation Of Cell Adhesion Response To Stimulus Protein Homotetramerization Transmembrane Transport Gap Junction-mediated Intercellular Transport	Cell-cell Signaling Visual Perception Transmembrane Transport Gap Junction-mediated Intercellular Transport
Pathways		Passive transport by Aquaporins	Gap junction assembly
Drugs		B-nonylglucoside
Diseases
GWAS		Axial length ( 24144296)	Body fat mass ( 28552196) Facial emotion recognition (happy faces) ( 28608620) Pericalcarine cortex volume ( 31530798)
Interacting Genes		47 interacting genes: AQP9 ATP6V0B CALM1 CD40 CISD2 CLDN5 CRYAA CRYAB CRYBB2 CRYGC ERGIC3 ERVFRD-1 FAM209A FCGR2A FOXA2 GJA3 GJA8 GJB5 GOLM1 GPX8 KCNJ6 LHFPL5 LMNA LRRC4C MFF MGST3 MRM3 MRPS18B MUC1 PDZK1IP1 PRKACA RELL2 SAR1A SGPL1 SLC14A1 SLC18A1 SSMEM1 STX1A STX2 SYAP1 SYT1 SYT2 TMEM139 TMEM154 TMEM52B TMX2 ZFPL1	5 interacting genes: CAV1 GJA1 MIP PRKCG TJP1
Entrez ID		4284	2700
HPRD ID		01098	00415
Ensembl ID		ENSG00000135517	ENSG00000121743
Uniprot IDs		P30301	Q9Y6H8
PDB IDs
Enriched GO Terms of Interacting Partners?
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