GJA3 and MIP

Data Source:
HPRD (in vivo)

		GJA3	MIP
Description		gap junction protein alpha 3	major intrinsic protein of lens fiber
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Connexin Complex	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Gap Junction Integral Component Of Membrane Apical Plasma Membrane
	Molecular Function	Gap Junction Channel Activity Gap Junction Hemi-channel Activity	Structural Constituent Of Eye Lens Protein Binding Calmodulin Binding Water Channel Activity
	Biological Process	Cell-cell Signaling Visual Perception Transmembrane Transport Gap Junction-mediated Intercellular Transport	Lens Development In Camera-type Eye Water Transport Visual Perception Positive Regulation Of Cell Adhesion Response To Stimulus Protein Homotetramerization Transmembrane Transport Gap Junction-mediated Intercellular Transport
Pathways		Gap junction assembly	Passive transport by Aquaporins
Drugs			B-nonylglucoside
Diseases
GWAS		Body fat mass ( 28552196) Facial emotion recognition (happy faces) ( 28608620) Pericalcarine cortex volume ( 31530798)	Axial length ( 24144296)
Interacting Genes		5 interacting genes: CAV1 GJA1 MIP PRKCG TJP1	47 interacting genes: AQP9 ATP6V0B CALM1 CD40 CISD2 CLDN5 CRYAA CRYAB CRYBB2 CRYGC ERGIC3 ERVFRD-1 FAM209A FCGR2A FOXA2 GJA3 GJA8 GJB5 GOLM1 GPX8 KCNJ6 LHFPL5 LMNA LRRC4C MFF MGST3 MRM3 MRPS18B MUC1 PDZK1IP1 PRKACA RELL2 SAR1A SGPL1 SLC14A1 SLC18A1 SSMEM1 STX1A STX2 SYAP1 SYT1 SYT2 TMEM139 TMEM154 TMEM52B TMX2 ZFPL1
Entrez ID		2700	4284
HPRD ID		00415	01098
Ensembl ID		ENSG00000121743	ENSG00000135517
Uniprot IDs		Q9Y6H8	P30301
PDB IDs
Enriched GO Terms of Interacting Partners?
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