LSS and SLC10A1

Data Source:
BioGRID (two hybrid)

		LSS	SLC10A1
Description		lanosterol synthase	solute carrier family 10 member 1
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Lipid Droplet Membrane	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane
	Molecular Function	Lanosterol Synthase Activity Protein Binding Beta-amyrin Synthase Activity	Virus Receptor Activity Protein Binding Bile Acid:sodium Symporter Activity
	Biological Process	Steroid Biosynthetic Process Cholesterol Biosynthetic Process Triterpenoid Biosynthetic Process Regulation Of Protein Stability Regulation Of Cholesterol Biosynthetic Process	Sodium Ion Transport Regulation Of Gene Expression Bile Acid And Bile Salt Transport Response To Nutrient Levels Cellular Response To Drug Bile Acid Signaling Pathway Response To Ethanol Viral Entry Into Host Cell Transmembrane Transport Regulation Of Bile Acid Secretion Response To 17alpha-ethynylestradiol
Pathways		Cholesterol biosynthesis Activation of gene expression by SREBF (SREBP)	Recycling of bile acids and salts
Drugs		R048-8071 Lanosterol
Diseases
GWAS		White blood cell count ( 27863252)	Daytime sleep phenotypes ( 27126917) Metabolite levels ( 23823483) Triglyceride levels ( 30108155)
Interacting Genes		9 interacting genes: AQP6 CIB1 GPR35 NR4A1 SLC10A1 SLC10A6 TMEM167B TMEM86B YIF1A	91 interacting genes: ABHD16A ACSL5 AGPAT3 ARL6IP6 ASGR1 ATP6V0B BMP10 C2 C8A CFHR5 CLDN19 CMTM3 COX20 CXCL9 CYB5R3 DERL1 DGAT2L6 FA2H FAM241B FAXDC2 FCER1G FDFT1 FXYD3 FXYD6 FXYD6-FXYD2 GAST GDE1 GIMAP5 GOSR2 GPR151 GPR152 IFITM2 IFITM3 IFTAP LRP10 LSS MAL MALL MFSD6 MS4A1 MYADML2 NEU1 NINJ2 ORMDL1 ORMDL2 ORMDL3 OTOP3 PEDS1-UBE2V1 PEX16 PKMYT1 RUSF1 SACM1L SCAMP4 SELENOK SFT2D1 SFT2D2 SFXN1 SLC12A7 SLC16A13 SLC25A46 SLC29A2 SLC35E4 SLC38A1 SLC38A7 SLC41A1 SLC66A2 SLC7A3 SMPD2 STX7 TAP1 TFRC TMBIM1 TMEM119 TMEM120B TMEM121 TMEM147 TMEM222 TMEM234 TMEM239 TMEM242 TMEM60 TMUB2 TOMM6 TRARG1 TSPO2 TVP23B UNC50 VAMP3 YIF1A YIPF4 YIPF6
Entrez ID		4047	6554
HPRD ID		02945	01672
Ensembl ID		ENSG00000160285	ENSG00000100652
Uniprot IDs		B2R694 P48449	B2RA41 Q14973
PDB IDs		1W6J 1W6K
Enriched GO Terms of Interacting Partners?
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