SLC10A1 and SMPD2

Data Source:
BioGRID (two hybrid)

		SLC10A1	SMPD2
Description		solute carrier family 10 member 1	sphingomyelin phosphodiesterase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Caveola Membrane Cell Periphery
	Molecular Function	Virus Receptor Activity Protein Binding Bile Acid:sodium Symporter Activity	Phospholipase Activity Sphingomyelin Phosphodiesterase Activity Protein Binding Metal Ion Binding
	Biological Process	Sodium Ion Transport Regulation Of Gene Expression Bile Acid And Bile Salt Transport Response To Nutrient Levels Cellular Response To Drug Bile Acid Signaling Pathway Response To Ethanol Viral Entry Into Host Cell Transmembrane Transport Regulation Of Bile Acid Secretion Response To 17alpha-ethynylestradiol	Sphingomyelin Metabolic Process Sphingomyelin Catabolic Process Glycosphingolipid Metabolic Process Response To Mechanical Stimulus Sphingolipid Catabolic Process Intracellular Signal Transduction Ceramide Biosynthetic Process Positive Regulation Of Ceramide Biosynthetic Process
Pathways		Recycling of bile acids and salts	Glycosphingolipid metabolism Ceramide signalling TNFR1-mediated ceramide production
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Metabolite levels ( 23823483) Triglyceride levels ( 30108155)	Height ( 18391951)
Interacting Genes		91 interacting genes: ABHD16A ACSL5 AGPAT3 ARL6IP6 ASGR1 ATP6V0B BMP10 C2 C8A CFHR5 CLDN19 CMTM3 COX20 CXCL9 CYB5R3 DERL1 DGAT2L6 FA2H FAM241B FAXDC2 FCER1G FDFT1 FXYD3 FXYD6 FXYD6-FXYD2 GAST GDE1 GIMAP5 GOSR2 GPR151 GPR152 IFITM2 IFITM3 IFTAP LRP10 LSS MAL MALL MFSD6 MS4A1 MYADML2 NEU1 NINJ2 ORMDL1 ORMDL2 ORMDL3 OTOP3 PEDS1-UBE2V1 PEX16 PKMYT1 RUSF1 SACM1L SCAMP4 SELENOK SFT2D1 SFT2D2 SFXN1 SLC12A7 SLC16A13 SLC25A46 SLC29A2 SLC35E4 SLC38A1 SLC38A7 SLC41A1 SLC66A2 SLC7A3 SMPD2 STX7 TAP1 TFRC TMBIM1 TMEM119 TMEM120B TMEM121 TMEM147 TMEM222 TMEM234 TMEM239 TMEM242 TMEM60 TMUB2 TOMM6 TRARG1 TSPO2 TVP23B UNC50 VAMP3 YIF1A YIPF4 YIPF6	15 interacting genes: ARFIP1 CCN1 COQ8A GAD2 NDRG4 PBX3 PGRMC2 PIK3CG PITPNC1 SLC10A1 SLC7A8 STAR TMEM14B TMEM167B TMEM31
Entrez ID		6554	6610
HPRD ID		01672	04608
Ensembl ID		ENSG00000100652	ENSG00000135587
Uniprot IDs		B2RA41 Q14973	O60906
PDB IDs
Enriched GO Terms of Interacting Partners?
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