RHOA and PRKCZ

  • Data Source:
  • HPRD (in vivo)

RHOA

PRKCZ

Description ras homolog family member A protein kinase C zeta
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood protein levels ( 28240269)
  • Brain morphology (min-P) ( 32665545)
  • Brain morphology (MOSTest) ( 32665545)
  • Cognitive function ( 25644384)
  • Coronary artery disease ( 29212778 28714974)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Cortical surface area (MOSTest) ( 32665545)
  • Crohn's disease ( 28067908)
  • Extremely high intelligence ( 29520040)
  • General cognitive ability ( 29844566)
  • Gut microbiota (functional units) ( 27694959)
  • Household income (MTAG) ( 31844048)
  • Inflammatory bowel disease ( 28067908)
  • Mood instability ( 31168069)
  • Morning person ( 30696823)
  • Refractive error ( 32231278)
  • Regular attendance at a religious group ( 29970889)
  • Sleep duration (short sleep) ( 30846698)
  • Subcortical volume (min-P) ( 32665545)
  • Subcortical volume (MOSTest) ( 32665545)
  • Ulcerative colitis ( 28067908)
  • Youthful appearance (self-reported) ( 32339537)
  • Body mass index ( 26426971)
  • Brain morphology (min-P) ( 32665545)
  • Brain morphology (MOSTest) ( 32665545)
  • Cortical surface area (min-P) ( 32665545)
  • Cortical surface area (MOSTest) ( 32665545)
  • Cortical thickness (min-P) ( 32665545)
  • Cortical thickness (MOSTest) ( 32665545)
  • General risk tolerance (MTAG) ( 30643258)
  • Height ( 20881960)
  • Response to antipsychotic treatment in schizophrenia (reasoning) ( 21107309)
  • Subcortical volume (min-P) ( 32665545)
  • Subcortical volume (MOSTest) ( 32665545)
Interacting Genes 124 interacting genes: AGAP1 AGAP2 AKAP13 ANKS1B ARAP2 ARHGAP1 ARHGAP10 ARHGAP11A ARHGAP11B ARHGAP19 ARHGAP20 ARHGAP21 ARHGAP22 ARHGAP23 ARHGAP26 ARHGAP29 ARHGAP31 ARHGAP32 ARHGAP40 ARHGAP5 ARHGAP8 ARHGDIA ARHGDIB ARHGDIG ARHGEF1 ARHGEF10 ARHGEF11 ARHGEF12 ARHGEF15 ARHGEF17 ARHGEF18 ARHGEF19 ARHGEF2 ARHGEF25 ARHGEF28 ARHGEF3 ARHGEF4 ARHGEF5 ARNTL BCR BIRC2 CAV1 CIT CLOCK CNKSR1 CNTNAP1 DAAM1 DCUN1D1 DEF6 DGKQ DIAPH1 DIAPH3 DLC1 DOCK7 DVL2 FLNA FMN2 GMIP HSPA1A ICMT IKBKG IKZF3 ITPR1 KCNA2 KCTD13 KTN1 LRP2 MCF2 MCF2L MPRIP MYO9A NET1 NGEF NOTCH1 OPHN1 OTUB1 PDE6D PITPNM1 PKN1 PKN2 PLCG1 PLD1 PLEKHG2 PLEKHG4 PLEKHG6 PPP1R12A PREX1 PREX2 PRKACA PRKCA PRKCZ PTPRF RABAC1 RACK1 RAP1GDS1 RASGRF1 RASGRF2 RASSF1 RHPN1 RHPN2 RIPK4 RIPOR2 RIPOR3 ROCK1 RPN2 RTKN SH3BP1 SLC13A1 SMAD2 SMURF1 SMURF2 SPRED2 SRGAP1 STARD8 TGFBR1 TGM2 TIAM1 TNFAIP1 TRIO TRIP6 TRPC1 VAV1 VAV2 VAV3 88 interacting genes: ADAP1 ADCY5 AFAP1 AKT1 AKT3 BLVRA BTK C1QBP CASP3 CASP6 CASP7 CASP8 CASP9 CCDC115 CDC42 CHAT CSNK2B DAPK3 DENND5A EGFR FADD FEZ1 FEZ2 FRS2 FYN GLRX3 GRB14 GRM5 GSK3A GSK3B H1-1 H1-5 HABP4 HDAC6 HRAS IKBKB IL4R IRAK1 IRS1 IRS4 JAK1 KRT10 LRRK2 MAP2K1 MAP2K5 MAPK1 MAPK3 MAPK7 MAPT MARCKS MBP NCF1 NCL NCOA3 NFATC2 NMT2 NUMB PARD6A PARD6B PARD6G PAWR PDLIM7 PDPK1 PEBP1 PIAS4 PPP1R14A PPP3CA PRG2 PRKCA PRKCD PSEN1 RAF1 RELA RHOA SLC39A1 SP1 SQSTM1 SRC STAT6 STUB1 TIAM1 TRAF6 UTP14A WWC1 YWHAB YWHAQ YWHAZ ZNF71
Entrez ID 387 5590
HPRD ID 01323 01504
Ensembl ID ENSG00000067560 ENSG00000067606
Uniprot IDs A0A024R324 B4DKN9 C9JRM1 C9JX21 P61586 Q9BVT0 Q05513
PDB IDs 1A2B 1CC0 1CXZ 1DPF 1FTN 1KMQ 1LB1 1OW3 1S1C 1TX4 1X86 1XCG 2RGN 3KZ1 3LW8 3LWN 3LXR 3MSX 3T06 4D0N 4XH9 4XOI 4XSG 4XSH 5A0F 5BWM 5C2K 5C4M 5EZ6 5FR1 5FR2 5HPY 5IRC 5JCP 5JHG 5JHH 5M6X 5M70 5ZHX 6BC0 6BCA 6BCB 6KX2 6KX3 6R3V
Enriched GO Terms of Interacting Partners?
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