Description |
inositol polyphosphate-5-phosphatase D |
KIT proto-oncogene, receptor tyrosine kinase |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Allergic disease (asthma, hay fever or eczema) ( 29083406)
- Alzheimer's disease (late onset) ( 30617256 24162737)
- Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
- Contrast sensitivity ( 24152035)
- Crohn's disease ( 22412388 23128233)
- Eosinophil counts ( 32888494 27863252)
- Eosinophil percentage of granulocytes ( 27863252)
- Eosinophil percentage of white cells ( 32888494 27863252)
- Family history of Alzheimer's disease ( 30617256)
- High light scatter reticulocyte count ( 32888494)
- High light scatter reticulocyte percentage of red cells ( 32888494)
- Immature fraction of reticulocytes ( 32888494)
- Neutrophil count ( 32888494)
- Neutrophil percentage of granulocytes ( 27863252)
- Perceived unattractiveness to mosquitoes ( 28199695)
- Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
- Sum eosinophil basophil counts ( 27863252)
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Interacting Genes |
45 interacting genes:
ARAP1
CD22
CD300LF
CRKL
CSF1R
CSF3R
CYSRT1
DAB1
DAB2
DOK1
DOK2
DOK3
EPOR
FCGR1B
FCGR2B
FGR
FLT3
GAB1
GAB2
GRB2
HCK
IL4R
JAK1
JAK3
KHDRBS3
KIT
KRT31
KRT40
KRTAP1-3
KRTAP10-3
KRTAP10-7
KRTAP10-9
KRTAP6-3
LILRB4
LYN
MET
NOTCH2NLA
PECAM1
PLCG1
PTPN11
SH3KBP1
SHC1
SLAMF1
XIAP
ZDHHC17
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92 interacting genes:
ABL1
ABL2
BCAR3
BLK
BLNK
BTK
CBL
CBLB
CD81
CD9
CISH
CLTC
CRK
CRKL
CSF1R
CSF2RA
CSF2RB
DOK1
EPOR
FES
FGR
FYN
GRAP
GRAP2
GRB10
GRB2
GRB7
HCK
HSH2D
IL7R
ILKAP
INPP5D
JAK2
JAK3
KITLG
LCK
LYN
MATK
MPDZ
NCK1
NCK2
PIK3CG
PIK3R1
PIK3R2
PIK3R3
PLCE1
PLCG1
PLCG2
PRKCA
PRKCB
PTK6
PTPN11
PTPN20
PTPN6
PTPRO
PTPRU
RASA1
SH2B2
SH2B3
SH2D1A
SH2D1B
SH2D2A
SH2D3C
SH3BP2
SHB
SHC1
SHC2
SHC3
SHC4
SLA2
SOCS1
SOCS2
SOCS3
SOCS5
SOCS6
SPRED1
SPRED2
SRC
STAP1
STAT1
STAT5A
STAT5B
STYX
SYK
TEC
TNS1
TNS2
TNS3
TXK
VAV3
YES1
ZAP70
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Entrez ID |
3635 |
3815 |
HPRD ID |
09033 |
01287 |
Ensembl ID |
ENSG00000168918
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ENSG00000157404
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Uniprot IDs |
Q92835
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A0A0U2N547
P10721
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PDB IDs |
2YSX
6IBD
6XY7
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1PKG
1QZJ
1QZK
1R01
1T45
1T46
2E9W
2EC8
2IUH
2VIF
3G0E
3G0F
4HVS
4K94
4K9E
4PGZ
4U0I
6GQJ
6GQK
6GQL
6GQM
6HH1
6ITT
6ITV
6KLA
6MOB
6XV9
6XVA
6XVB
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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