Description |
inositol polyphosphate-5-phosphatase D |
HCK proto-oncogene, Src family tyrosine kinase |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Allergic disease (asthma, hay fever or eczema) ( 29083406)
- Alzheimer's disease (late onset) ( 30617256 24162737)
- Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
- Contrast sensitivity ( 24152035)
- Crohn's disease ( 22412388 23128233)
- Eosinophil counts ( 32888494 27863252)
- Eosinophil percentage of granulocytes ( 27863252)
- Eosinophil percentage of white cells ( 32888494 27863252)
- Family history of Alzheimer's disease ( 30617256)
- High light scatter reticulocyte count ( 32888494)
- High light scatter reticulocyte percentage of red cells ( 32888494)
- Immature fraction of reticulocytes ( 32888494)
- Neutrophil count ( 32888494)
- Neutrophil percentage of granulocytes ( 27863252)
- Perceived unattractiveness to mosquitoes ( 28199695)
- Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
- Sum eosinophil basophil counts ( 27863252)
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- Adult body size ( 32376654)
- Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143)
- Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
- Inflammatory bowel disease ( 23128233)
- Migraine ( 27322543)
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Interacting Genes |
45 interacting genes:
ARAP1
CD22
CD300LF
CRKL
CSF1R
CSF3R
CYSRT1
DAB1
DAB2
DOK1
DOK2
DOK3
EPOR
FCGR1B
FCGR2B
FGR
FLT3
GAB1
GAB2
GRB2
HCK
IL4R
JAK1
JAK3
KHDRBS3
KIT
KRT31
KRT40
KRTAP1-3
KRTAP10-3
KRTAP10-7
KRTAP10-9
KRTAP6-3
LILRB4
LYN
MET
NOTCH2NLA
PECAM1
PLCG1
PTPN11
SH3KBP1
SHC1
SLAMF1
XIAP
ZDHHC17
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116 interacting genes:
ABL1
ABL2
ACTB
ADAM15
AGK
AGR2
APP
AR
ARRB1
ASAP1
BCAR1
BCR
BPIFA1
BTK
CBL
CCDC88B
CCR3
CD2AP
CHST15
CREBBP
CSF2RB
CSF3R
CSK
CTAG1A
CTAG1B
CYB5D2
CYSRT1
DNM2
DOK1
DOK2
EGFR
ELMO1
ERBB2
ERBB3
ERBB4
EVL
FASLG
FCGR1A
FCGR2A
FHL2
FHL5
GAB1
GOPC
GRB14
HNRNPK
HSF2BP
IL6ST
INCA1
INPP5D
IRF2BPL
KHDRBS1
KIT
KPRP
KRT31
KRT34
KRT35
KRT36
KRT40
KRTAP1-1
KRTAP1-3
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP3-1
LCP2
LETMD1
LMNA
MAP4K5
MDK
MDM2
MET
MID2
MKRN3
MTUS2
NBPF19
NGEF
NOTCH2NLA
PAK2
PECAM1
PIK3CB
PIK3R1
PIK3R2
PLAUR
PLCG1
PLCG2
PLEKHG4
PNMA1
RAPGEF1
RASA1
RASA3
RBPMS
RPL10
SF3B3
SH2B2
SH3BP1
SH3KBP1
SKAP2
SOS1
SPRR2A
STAT3
TEKT4
TEPSIN
TNK2
TOX2
TP73
TRIM27
TRIP6
TRPV4
TSG101
UNC119
VAV1
WAS
WDCP
WIPF1
WNT2
ZSCAN4
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Entrez ID |
3635 |
3055 |
HPRD ID |
09033 |
00796 |
Ensembl ID |
ENSG00000168918
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ENSG00000101336
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Uniprot IDs |
Q92835
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A8K4G3
P08631
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PDB IDs |
2YSX
6IBD
6XY7
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1AD5
1BU1
1QCF
2C0I
2C0O
2C0T
2HCK
2HK5
2OI3
2OJ2
3HCK
3NHN
3RBB
3REA
3REB
3VRY
3VRZ
3VS0
3VS1
3VS2
3VS3
3VS4
3VS5
3VS6
3VS7
4HCK
4LUD
4LUE
4ORZ
4U5W
5H09
5H0B
5H0E
5H0G
5H0H
5HCK
5NUH
5ZJ6
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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