IL10RA and NIPAL4

Data Source:
BioGRID (two hybrid)

		IL10RA	NIPAL4
Description		interleukin 10 receptor subunit alpha	NIPA like domain containing 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Integral Component Of Membrane	Membrane Integral Component Of Membrane
	Molecular Function	Cytokine Receptor Activity Interleukin-10 Receptor Activity Protein Binding Interleukin-10 Binding Signaling Receptor Activity	Protein Binding Magnesium Ion Transmembrane Transporter Activity
	Biological Process	Negative Regulation Of Autophagy Cytokine-mediated Signaling Pathway Response To Lipopolysaccharide Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Regulation Of Synapse Organization Ubiquitin-dependent Endocytosis	Magnesium Ion Transport Magnesium Ion Transmembrane Transport
Pathways		Interleukin-10 signaling	Miscellaneous transport and binding events
Drugs
Diseases			Lamellar ichthyosis (LI) and Non-bullous congenital ichthyosiform erythroderma (NBCIE)
GWAS		Obesity-related traits ( 23251661)	Asthma ( 31959851)
Interacting Genes		20 interacting genes: BTRC C1QL4 CDS2 CMTM3 HACD1 IL10 IL10RB JAK1 MAL NIPAL4 PLPP6 RUSF1 SELENOK SLC38A7 SLC66A2 SLC7A14 SMCO4 TMEM242 TMUB2 YIPF6	15 interacting genes: ACKR2 CLDN7 CMTM2 COMT FFAR2 GJB1 GPR152 HHLA2 IL10RA LHFPL5 RNF185 RNF19B SSMEM1 TM4SF18 TRHR
Entrez ID		3587	348938
HPRD ID		00911	19424
Ensembl ID		ENSG00000110324	ENSG00000172548
Uniprot IDs		Q13651	Q0D2K0
PDB IDs		1J7V 1LQS 1Y6K 1Y6M 1Y6N 5IXI
Enriched GO Terms of Interacting Partners?
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