NIPAL4 and RNF19B

Data Source:
BioGRID (two hybrid)

		NIPAL4	RNF19B
Description		NIPA like domain containing 4	ring finger protein 19B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane Integral Component Of Membrane	Ubiquitin Ligase Complex Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane Cytolytic Granule
	Molecular Function	Protein Binding Magnesium Ion Transmembrane Transporter Activity	Protein Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Magnesium Ion Transport Magnesium Ion Transmembrane Transport	Protein Polyubiquitination Adaptive Immune Response Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Natural Killer Cell Mediated Cytotoxicity Protein Autoubiquitination
Pathways		Miscellaneous transport and binding events	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases		Lamellar ichthyosis (LI) and Non-bullous congenital ichthyosiform erythroderma (NBCIE)
GWAS		Asthma ( 31959851)	Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269)
Interacting Genes		15 interacting genes: ACKR2 CLDN7 CMTM2 COMT FFAR2 GJB1 GPR152 HHLA2 IL10RA LHFPL5 RNF185 RNF19B SSMEM1 TM4SF18 TRHR	31 interacting genes: AP1M1 APOL3 ASGR1 CDIPT CLEC1A DHODH FDPS GIMAP5 GOSR2 ICMT MEST MFSD5 MS4A1 NIPAL4 PPP1CC RAP1GDS1 SACM1L SEC22A SEC23A SELENOK SLC30A3 TAP1 TMEM100 TMEM120B TMEM208 TMEM31 TNF TSPAN2 UBE2D2 UBE2D3 UBE2L3
Entrez ID		348938	127544
HPRD ID		19424	13725
Ensembl ID		ENSG00000172548	ENSG00000116514
Uniprot IDs		Q0D2K0	Q6ZMZ0
PDB IDs
Enriched GO Terms of Interacting Partners?
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