NIPAL4 and RNF185

Data Source:
BioGRID (two hybrid)

		NIPAL4	RNF185
Description		NIPA like domain containing 4	ring finger protein 185
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane Integral Component Of Membrane	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	Protein Binding Magnesium Ion Transmembrane Transporter Activity	Protein Binding Ubiquitin Binding Ubiquitin-like Protein Conjugating Enzyme Binding Protein-containing Complex Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Magnesium Ion Transport Magnesium Ion Transmembrane Transport	Ubiquitin-dependent Protein Catabolic Process Autophagy Ubiquitin-dependent ERAD Pathway ERAD Pathway Protein Autoubiquitination Transmembrane Transport ER-associated Misfolded Protein Catabolic Process Positive Regulation Of ERAD Pathway Endoplasmic Reticulum Mannose Trimming
Pathways		Miscellaneous transport and binding events	ABC-family proteins mediated transport Defective CFTR causes cystic fibrosis ER Quality Control Compartment (ERQC)
Drugs
Diseases		Lamellar ichthyosis (LI) and Non-bullous congenital ichthyosiform erythroderma (NBCIE)
GWAS		Asthma ( 31959851)	Apolipoprotein A1 levels ( 32203549) Fish- and plant-related diet ( 32066663) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Waist circumference ( 28552196) White blood cell count ( 32888494)
Interacting Genes		15 interacting genes: ACKR2 CLDN7 CMTM2 COMT FFAR2 GJB1 GPR152 HHLA2 IL10RA LHFPL5 RNF185 RNF19B SSMEM1 TM4SF18 TRHR	32 interacting genes: APP CGAS CMTM5 CYB561A3 DVL2 FAM241B MALL MS4A13 MTNR1B MYADML2 NIPAL4 RNF5 TMBIM6 TMEM147 TMEM19 TMEM86A UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2V1 UBE2W USP21 YIPF2 YIPF4 YIPF6
Entrez ID		348938	91445
HPRD ID		19424	08790
Ensembl ID		ENSG00000172548	ENSG00000138942
Uniprot IDs		Q0D2K0	A0A024R1F5 A0A024R1H4 Q96GF1
PDB IDs
Enriched GO Terms of Interacting Partners?
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