HSPA6 and LGALS7B

Data Source:
BioGRID (two hybrid)

		HSPA6	LGALS7B
Description		heat shock protein family A (Hsp70) member 6	galectin 7B
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Centriole Cytosol Plasma Membrane COP9 Signalosome Secretory Granule Lumen Extracellular Exosome Blood Microparticle Ficolin-1-rich Granule Lumen	Extracellular Space Nucleus Cytosol Extracellular Exosome
	Molecular Function	Protein Binding ATP Binding ATPase Activity Enzyme Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Protein Folding Chaperone Unfolded Protein Binding Misfolded Protein Binding	Protein Binding Galactoside Binding Carbohydrate Binding
	Biological Process	Response To Unfolded Protein Vesicle-mediated Transport Cellular Response To Heat Cellular Response To Unfolded Protein Protein Refolding Neutrophil Degranulation Chaperone Cofactor-dependent Protein Refolding Cellular Heat Acclimation	Apoptotic Process Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Positive Regulation Of Gene Expression Negative Regulation Of Interferon-gamma Production Negative Regulation Of CD4-positive, Alpha-beta T Cell Proliferation
Pathways		Regulation of HSF1-mediated heat shock response Neutrophil degranulation
Drugs			Beta-D-Glucose beta-D-Galactosamine
Diseases
GWAS		Birth weight ( 31043758) Blood protein levels ( 28240269) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Functional impairment in major depressive disorder, bipolar disorder and schizophrenia ( 24039173) Helicobacter pylori serologic status ( 23652523) Inflammatory bowel disease ( 28067908 23128233) Offspring birth weight ( 31043758) Ulcerative colitis ( 28067908 21297633)	Logical memory (immediate recall) in mild cognitive impairment ( 29274321)
Interacting Genes		16 interacting genes: ADCK5 AHCYL1 BAG4 C22orf15 CISH COMMD6 CYP4F12 DNAJB4 FLNA KRT222 LGALS7 LGALS7B PPIB PRAP1 RPA1 TERF1	6 interacting genes: HSPA6 LSM2 SSBP1 TAB1 TGM5 YAF2
Entrez ID		3310	653499
HPRD ID		00775	19145
Ensembl ID		ENSG00000173110	ENSG00000178934
Uniprot IDs		A0A384NKX5 B3KSM6 P17066	P47929
PDB IDs		3FE1	1BKZ 2GAL 3GAL 3ZXE 3ZXF 4GAL 4UW3 4UW4 4UW5 4UW6 4XBQ 4Y26 5GAL 5H9Q 5H9S
Enriched GO Terms of Interacting Partners?
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