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HPCA and UQCRB
Data Source:
BioGRID
(two hybrid)
HPCA
UQCRB
Description
hippocalcin
ubiquinol-cytochrome c reductase binding protein
Image
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Extrinsic Component Of Membrane
Axon
Dendrite Membrane
Neuronal Cell Body Membrane
Dendrite Cytoplasm
Perikaryon
Dendritic Spine Head
Glutamatergic Synapse
Mitochondrial Inner Membrane
Mitochondrial Respirasome
Mitochondrial Respiratory Chain Complex III
Molecular Function
Actin Binding
Calcium Ion Binding
Protein Binding
Kinase Binding
Identical Protein Binding
Protein Binding
Biological Process
Brain Development
Calcium-mediated Signaling
Negative Regulation Of Guanylate Cyclase Activity
Activation Of Phospholipase D Activity
Positive Regulation Of Adenylate Cyclase Activity
Inner Ear Development
Retina Development In Camera-type Eye
Cellular Response To Electrical Stimulus
Cellular Response To Calcium Ion
Positive Regulation Of Protein Targeting To Membrane
Regulation Of Postsynaptic Neurotransmitter Receptor Internalization
Regulation Of Voltage-gated Calcium Channel Activity
Response To Ketamine
Response To L-glutamate
Cellular Response To Monosodium Glutamate
Response To Aroclor 1254
Oxidative Phosphorylation
Mitochondrial Electron Transport, Ubiquinol To Cytochrome C
Aerobic Respiration
Pathways
Respiratory electron transport
Drugs
2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol
6-Hydroxy-5-undecyl-4,7-benzothiazoledione
Azoxystrobin
5-Heptyl-6-hydroxy-1,3-benzothiazole-4,7-dione
(5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE
(S)-famoxadone
METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE
2-Nonyl-4-quinolinol 1-oxide
Ubiquinone Q2
Diseases
Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS
Huntington's disease progression (
28642124
)
Interacting Genes
16 interacting genes:
C1QTNF2
CKMT1A
CKMT1B
CREM
DTX2
GATA5
IL36RN
MLLT10
MYDGF
NAIP
NMT1
PRR35
SLC16A3
TEPSIN
UQCRB
VWC2
9 interacting genes:
ACAP1
ACCS
HPCA
HSPB1
LRRK2
MAGEA1
MAGEA4
MAGEB4
ZSWIM7
Entrez ID
3208
7381
HPRD ID
00811
11770
Ensembl ID
ENSG00000121905
ENSG00000156467
Uniprot IDs
P84074
P14927
PDB IDs
5G4P
5G58
5M6C
5XTE
5XTH
5XTI
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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