HNRNPAB and USP19

Data Source:
BioGRID (two hybrid)

		HNRNPAB	USP19
Description		heterogeneous nuclear ribonucleoprotein A/B	ubiquitin specific peptidase 19
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm RNA Polymerase II Transcription Regulator Complex Ribonucleoprotein Complex	Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane
	Molecular Function	RNA Binding MRNA Binding Protein Binding	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity Ubiquitin Protein Ligase Binding Metal Ion Binding Hsp90 Protein Binding Lys48-specific Deubiquitinase Activity
	Biological Process	Epithelial To Mesenchymal Transition Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated	Protein Deubiquitination Protein Phosphopantetheinylation Ubiquitin-dependent ERAD Pathway Regulation Of Protein Stability Response To Endoplasmic Reticulum Stress Negative Regulation Of Skeletal Muscle Tissue Development Protein Stabilization Protein K48-linked Deubiquitination Positive Regulation Of Cell Cycle Process Regulation Of Cellular Response To Hypoxia Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of ERAD Pathway
Pathways			Ub-specific processing proteases
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Immature fraction of reticulocytes ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		19 interacting genes: ACTB CDC42 DEDD2 ELAVL2 ERG H3-4 H3C1 HMGA1 HOXC13 HOXD4 IL7R POLR3D PTBP1 PTBP2 PTEN RBFOX2 TP63 USP19 YWHAG	13 interacting genes: BIRC3 CKAP5 ECEL1 FLNA HIF1A HNRNPAB HSP90AA1 LAMTOR4 RNF2 SIAH1 SIAH2 SNRNP200 UBC
Entrez ID		3182	10869
HPRD ID		04067	18278
Ensembl ID		ENSG00000197451	ENSG00000172046
Uniprot IDs		Q99729	O94966
PDB IDs		3S7R	1WH0 4X3G 6K7W 6KHV 6KQV
Enriched GO Terms of Interacting Partners?
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