POLR1H and TRIML2

Data Source:
BioGRID (two hybrid)

		POLR1H	TRIML2
Description		RNA polymerase I subunit H	tripartite motif family like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm RNA Polymerase I Complex	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Nucleic Acid Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Zinc Ion Binding	Protein Binding Protein Kinase Binding Identical Protein Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity
	Biological Process	Nucleobase-containing Compound Metabolic Process Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription MRNA Cleavage Positive Regulation Of Gene Expression, Epigenetic	Protein Polyubiquitination Regulation Of Gene Expression Positive Regulation Of Autophagy Protein Ubiquitination Response To Retinoic Acid Regulation Of Protein Localization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Regulation Of Viral Entry Into Host Cell Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways		NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS			Polycystic ovary syndrome ( 25574032)
Interacting Genes		18 interacting genes: APOA1 ATXN2 CIC DUSP1 FHL3 GFI1B GPR20 HAX1 IL15 IVNS1ABP MAPK8IP2 NONO SACS SERPINA3 TNS2 TRIML2 UBE2I ZNF593	48 interacting genes: ABI2 BLOC1S2 CBY2 CCDC146 CCDC92 CCHCR1 CCNH CDR2 CTBP2 EIF2B1 EIF3M FAM90A1 FAM9C HGS ING5 ITGB3BP KRT15 KRT24 KRT27 KRT31 KRT34 KRT38 KRT75 MBD3L2 MBD3L3 MEOX1 MEOX2 NECAB2 NFKBID NUP62 PICK1 POLR1H POU6F2 SH2D4A STN1 SUMO2 SYCE2 TBC1D25 TCF4 TFIP11 TRIM54 TSEN54 TSG101 USHBP1 XAF1 ZBED1 ZBTB33 ZFHX3
Entrez ID		30834	205860
HPRD ID		09601	08696
Ensembl ID		ENSG00000066379	ENSG00000179046
Uniprot IDs		Q2L6J2 Q9P1U0	B7ZLC3 Q8N7C3
PDB IDs
Enriched GO Terms of Interacting Partners?
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