TRIML2 and TBC1D25

Data Source:
BioGRID (two hybrid)

		TRIML2	TBC1D25
Description		tripartite motif family like 2	TBC1 domain family member 25
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol	Autophagosome Cytoplasmic Vesicle
	Molecular Function	Protein Binding Protein Kinase Binding Identical Protein Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity	GTPase Activator Activity Protein Binding
	Biological Process	Protein Polyubiquitination Regulation Of Gene Expression Positive Regulation Of Autophagy Protein Ubiquitination Response To Retinoic Acid Regulation Of Protein Localization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Regulation Of Viral Entry Into Host Cell Positive Regulation Of NF-kappaB Transcription Factor Activity	Intracellular Protein Transport Autophagy Activation Of GTPase Activity Regulation Of Autophagosome Maturation
Pathways			TBC/RABGAPs
Drugs
Diseases
GWAS		Polycystic ovary syndrome ( 25574032)
Interacting Genes		48 interacting genes: ABI2 BLOC1S2 CBY2 CCDC146 CCDC92 CCHCR1 CCNH CDR2 CTBP2 EIF2B1 EIF3M FAM90A1 FAM9C HGS ING5 ITGB3BP KRT15 KRT24 KRT27 KRT31 KRT34 KRT38 KRT75 MBD3L2 MBD3L3 MEOX1 MEOX2 NECAB2 NFKBID NUP62 PICK1 POLR1H POU6F2 SH2D4A STN1 SUMO2 SYCE2 TBC1D25 TCF4 TFIP11 TRIM54 TSEN54 TSG101 USHBP1 XAF1 ZBED1 ZBTB33 ZFHX3	16 interacting genes: FAM9B FEZ1 FEZ2 GABARAP GABARAPL1 GABARAPL2 KCNIP1 LARP1B LGALS14 LMNTD2 MAP1LC3A MAP1LC3B MAP1LC3C RAB2A RUSC1 TRIML2
Entrez ID		205860	4943
HPRD ID		08696	08948
Ensembl ID		ENSG00000179046	ENSG00000068354
Uniprot IDs		B7ZLC3 Q8N7C3	B4DF03 Q3MII6
PDB IDs
Enriched GO Terms of Interacting Partners?
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