TRIML2 and SYCE2

Data Source:
BioGRID (two hybrid)

		TRIML2	SYCE2
Description		tripartite motif family like 2	synaptonemal complex central element protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol	Central Element Nucleoplasm Chromosome
	Molecular Function	Protein Binding Protein Kinase Binding Identical Protein Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Protein Polyubiquitination Regulation Of Gene Expression Positive Regulation Of Autophagy Protein Ubiquitination Response To Retinoic Acid Regulation Of Protein Localization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Regulation Of Viral Entry Into Host Cell Positive Regulation Of NF-kappaB Transcription Factor Activity	Synaptonemal Complex Assembly Cell Division
Pathways			Meiotic synapsis
Drugs
Diseases
GWAS		Polycystic ovary syndrome ( 25574032)	Clozapine-induced agranulocytosis ( 25187353) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494) Red blood cell traits ( 23222517) Red cell distribution width ( 32888494)
Interacting Genes		48 interacting genes: ABI2 BLOC1S2 CBY2 CCDC146 CCDC92 CCHCR1 CCNH CDR2 CTBP2 EIF2B1 EIF3M FAM90A1 FAM9C HGS ING5 ITGB3BP KRT15 KRT24 KRT27 KRT31 KRT34 KRT38 KRT75 MBD3L2 MBD3L3 MEOX1 MEOX2 NECAB2 NFKBID NUP62 PICK1 POLR1H POU6F2 SH2D4A STN1 SUMO2 SYCE2 TBC1D25 TCF4 TFIP11 TRIM54 TSEN54 TSG101 USHBP1 XAF1 ZBED1 ZBTB33 ZFHX3	13 interacting genes: CCDC196 CDC37 GAD2 HOMER1 IFT20 KIFC3 MED11 MED4 NAP1L5 TEX12 TRIM69 TRIML2 TSNAX
Entrez ID		205860	256126
HPRD ID		08696	19522
Ensembl ID		ENSG00000179046	ENSG00000161860
Uniprot IDs		B7ZLC3 Q8N7C3	Q6PIF2
PDB IDs			6R17
Enriched GO Terms of Interacting Partners?
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