TRIML2 and CCDC92

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		TRIML2	CCDC92
Description		tripartite motif family like 2	coiled-coil domain containing 92
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol	Nucleoplasm Cytoplasm Centrosome Centriole Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Protein Kinase Binding Identical Protein Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity	Protein Binding Identical Protein Binding
	Biological Process	Protein Polyubiquitination Regulation Of Gene Expression Positive Regulation Of Autophagy Protein Ubiquitination Response To Retinoic Acid Regulation Of Protein Localization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Regulation Of Viral Entry Into Host Cell Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways
Drugs
Diseases
GWAS		Polycystic ovary syndrome ( 25574032)	Atrial fibrillation ( 29892015) Coronary artery disease ( 29212778 28714974) Hand grip strength ( 29691431) HDL cholesterol ( 20686565) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference ( 31453325) Hip circumference variance ( 31453325) Lymphocyte counts ( 32888494) Metabolite levels ( 23823483) Monocyte count ( 32888494) Red blood cell count ( 32888494) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494) Triglyceride levels ( 32203549) Triglycerides ( 20686565) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference variance ( 31453325) Waist-to-hip ratio adjusted for BMI ( 26426971 30389748) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500) White blood cell count ( 32888494 27863252)
Interacting Genes		48 interacting genes: ABI2 BLOC1S2 CBY2 CCDC146 CCDC92 CCHCR1 CCNH CDR2 CTBP2 EIF2B1 EIF3M FAM90A1 FAM9C HGS ING5 ITGB3BP KRT15 KRT24 KRT27 KRT31 KRT34 KRT38 KRT75 MBD3L2 MBD3L3 MEOX1 MEOX2 NECAB2 NFKBID NUP62 PICK1 POLR1H POU6F2 SH2D4A STN1 SUMO2 SYCE2 TBC1D25 TCF4 TFIP11 TRIM54 TSEN54 TSG101 USHBP1 XAF1 ZBED1 ZBTB33 ZFHX3	12 interacting genes: CEP76 CHGB COG6 DISC1 FHL2 GOLGA2 PLEKHA5 PSMD8 TP53BP2 TRIM27 TRIML2 UBC
Entrez ID		205860	80212
HPRD ID		08696	16919
Ensembl ID		ENSG00000179046	ENSG00000119242
Uniprot IDs		B7ZLC3 Q8N7C3	Q53HC0
PDB IDs
Enriched GO Terms of Interacting Partners?
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