H1-4 and CBX1

Data Source:
HPRD (in vitro)

		H1-4	CBX1
Description		H1.4 linker histone, cluster member	chromobox 1
Image
GO Annotations	Cellular Component	Nucleosome Heterochromatin Nucleus	Chromosome, Centromeric Region Chromosome, Telomeric Region Chromatin Heterochromatin Female Pronucleus Male Pronucleus Nucleus Nucleoplasm Pericentric Heterochromatin Spindle Chromocenter Site Of DNA Damage
	Molecular Function	Double-stranded DNA Binding RNA Binding Calcium Ion Binding Protein Binding ATP Binding GTP Binding AMP Binding Chromatin DNA Binding Nucleosomal DNA Binding DATP Binding ADP Binding	Chromatin Binding Protein Binding Enzyme Binding Identical Protein Binding Histone Methyltransferase Binding
	Biological Process	Nucleosome Assembly Nucleosome Positioning Chromosome Condensation Negative Regulation Of Chromatin Silencing Negative Regulation Of DNA Recombination	Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated
Pathways		Apoptosis induced DNA fragmentation Formation of Senescence-Associated Heterochromatin Foci (SAHF)	HCMV Early Events
Drugs		Copper
Diseases
GWAS			Body mass index ( 26426971 20935630) Generalized epilepsy ( 22949513)
Interacting Genes		6 interacting genes: CBX1 CBX3 CBX5 IL7R IRAK4 PRKCA	36 interacting genes: ABI3BP ARL5A ATXN7L2 BAHD1 BARD1 BRCA1 CBX3 CBX5 CHAF1A DNMT1 DNMT3A DNMT3B EMSY H1-4 H3-4 H3C1 H3C3 HECW2 HSPB1 KLF11 LNX1 LRIF1 NR2F6 NSL1 PCNA PIM1 RB1 RPL12 SP100 SUV39H1 TRIM24 TRIM28 UCHL1 VHL VTN ZNF280C
Entrez ID		3008	10951
HPRD ID		07513	05149
Ensembl ID		ENSG00000168298	ENSG00000108468
Uniprot IDs		A3R0T8 P10412	P83916 Q6IBN6
PDB IDs		3TZD 5JJZ 6H8P	2FMM 3F2U 3Q6S 5T1G 6D07 6D08
Enriched GO Terms of Interacting Partners?
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