CBX1 and NSL1

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		CBX1	NSL1
Description		chromobox 1	NSL1 component of MIS12 kinetochore complex
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromosome, Telomeric Region Chromatin Heterochromatin Female Pronucleus Male Pronucleus Nucleus Nucleoplasm Pericentric Heterochromatin Spindle Chromocenter Site Of DNA Damage	MIS12/MIND Type Complex Condensed Chromosome Kinetochore Cytosol Nuclear Speck
	Molecular Function	Chromatin Binding Protein Binding Enzyme Binding Identical Protein Binding Histone Methyltransferase Binding	Protein Binding
	Biological Process	Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated	Mitotic Sister Chromatid Segregation Cell Division
Pathways		HCMV Early Events	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Body mass index ( 26426971 20935630) Generalized epilepsy ( 22949513)
Interacting Genes		36 interacting genes: ABI3BP ARL5A ATXN7L2 BAHD1 BARD1 BRCA1 CBX3 CBX5 CHAF1A DNMT1 DNMT3A DNMT3B EMSY H1-4 H3-4 H3C1 H3C3 HECW2 HSPB1 KLF11 LNX1 LRIF1 NR2F6 NSL1 PCNA PIM1 RB1 RPL12 SP100 SUV39H1 TRIM24 TRIM28 UCHL1 VHL VTN ZNF280C	9 interacting genes: CBX1 CBX3 CBX5 DSN1 G6PC1 HSP90AA1 LRRK2 MIS12 SUGT1
Entrez ID		10951	25936
HPRD ID		05149	12378
Ensembl ID		ENSG00000108468	ENSG00000117697
Uniprot IDs		P83916 Q6IBN6	Q53FM2 Q5SY74 Q96IY1
PDB IDs		2FMM 3F2U 3Q6S 5T1G 6D07 6D08	4NF9 5LSI 5LSJ 5LSK
Enriched GO Terms of Interacting Partners?
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