CBX1 and H1-4

Data Source:
HPRD (in vitro)

		CBX1	H1-4
Description		chromobox 1	H1.4 linker histone, cluster member
Image
GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromosome, Telomeric Region Chromatin Heterochromatin Female Pronucleus Male Pronucleus Nucleus Nucleoplasm Pericentric Heterochromatin Spindle Chromocenter Site Of DNA Damage	Nucleosome Heterochromatin Nucleus
	Molecular Function	Chromatin Binding Protein Binding Enzyme Binding Identical Protein Binding Histone Methyltransferase Binding	Double-stranded DNA Binding RNA Binding Calcium Ion Binding Protein Binding ATP Binding GTP Binding AMP Binding Chromatin DNA Binding Nucleosomal DNA Binding DATP Binding ADP Binding
	Biological Process	Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated	Nucleosome Assembly Nucleosome Positioning Chromosome Condensation Negative Regulation Of Chromatin Silencing Negative Regulation Of DNA Recombination
Pathways		HCMV Early Events	Apoptosis induced DNA fragmentation Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs			Copper
Diseases
GWAS		Body mass index ( 26426971 20935630) Generalized epilepsy ( 22949513)
Interacting Genes		36 interacting genes: ABI3BP ARL5A ATXN7L2 BAHD1 BARD1 BRCA1 CBX3 CBX5 CHAF1A DNMT1 DNMT3A DNMT3B EMSY H1-4 H3-4 H3C1 H3C3 HECW2 HSPB1 KLF11 LNX1 LRIF1 NR2F6 NSL1 PCNA PIM1 RB1 RPL12 SP100 SUV39H1 TRIM24 TRIM28 UCHL1 VHL VTN ZNF280C	6 interacting genes: CBX1 CBX3 CBX5 IL7R IRAK4 PRKCA
Entrez ID		10951	3008
HPRD ID		05149	07513
Ensembl ID		ENSG00000108468	ENSG00000168298
Uniprot IDs		P83916 Q6IBN6	A3R0T8 P10412
PDB IDs		2FMM 3F2U 3Q6S 5T1G 6D07 6D08	3TZD 5JJZ 6H8P
Enriched GO Terms of Interacting Partners?
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