CBX1 and RPL12

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CBX1	RPL12
Description		chromobox 1	ribosomal protein L12
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromosome, Telomeric Region Chromatin Heterochromatin Female Pronucleus Male Pronucleus Nucleus Nucleoplasm Pericentric Heterochromatin Spindle Chromocenter Site Of DNA Damage	Cytosol Focal Adhesion Postsynaptic Density Large Ribosomal Subunit Membrane Cytosolic Large Ribosomal Subunit Extracellular Exosome
	Molecular Function	Chromatin Binding Protein Binding Enzyme Binding Identical Protein Binding Histone Methyltransferase Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding Large Ribosomal Subunit RRNA Binding
	Biological Process	Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription
Pathways		HCMV Early Events	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Body mass index ( 26426971 20935630) Generalized epilepsy ( 22949513)
Interacting Genes		36 interacting genes: ABI3BP ARL5A ATXN7L2 BAHD1 BARD1 BRCA1 CBX3 CBX5 CHAF1A DNMT1 DNMT3A DNMT3B EMSY H1-4 H3-4 H3C1 H3C3 HECW2 HSPB1 KLF11 LNX1 LRIF1 NR2F6 NSL1 PCNA PIM1 RB1 RPL12 SP100 SUV39H1 TRIM24 TRIM28 UCHL1 VHL VTN ZNF280C	9 interacting genes: APP CBX1 DUX4 IPO11 OR10G4 PAXIP1 PTEN TTN UBC
Entrez ID		10951	6136
HPRD ID		05149	01603
Ensembl ID		ENSG00000108468	ENSG00000197958
Uniprot IDs		P83916 Q6IBN6	P30050
PDB IDs		2FMM 3F2U 3Q6S 5T1G 6D07 6D08	4V6X 5A8L 5AJ0 6OLG 6ZM7 6ZME 6ZMI 6ZMO
Enriched GO Terms of Interacting Partners?
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