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GNAQ and ADRA1B
Data Source:
HPRD
(in vivo)
GNAQ
ADRA1B
Description
G protein subunit alpha q
adrenoceptor alpha 1B
Image
No pdb structure
GO Annotations
Cellular Component
Photoreceptor Outer Segment
Cytoplasm
Lysosomal Membrane
Golgi Apparatus
Heterotrimeric G-protein Complex
Plasma Membrane
Nuclear Membrane
Synapse
Extracellular Exosome
Nucleus
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Caveola
Nuclear Membrane
Molecular Function
G Protein-coupled Receptor Binding
GTPase Activity
GTPase Activator Activity
Protein Binding
GTP Binding
G-protein Beta/gamma-subunit Complex Binding
Type 2A Serotonin Receptor Binding
Metal Ion Binding
G Protein-coupled Receptor Activity
Alpha1-adrenergic Receptor Activity
Protein Binding
Protein Heterodimerization Activity
Biological Process
Action Potential
Negative Regulation Of Protein Kinase Activity
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Activation Of Phospholipase C Activity
G Protein-coupled Acetylcholine Receptor Signaling Pathway
Glutamate Receptor Signaling Pathway
Blood Coagulation
Phototransduction, Visible Light
Entrainment Of Circadian Clock
Platelet Activation
Positive Regulation Of GTPase Activity
Protein Stabilization
Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Heart Rate By Epinephrine-norepinephrine
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Cell-cell Signaling
Intracellular Signal Transduction
Positive Regulation Of MAPK Cascade
Positive Regulation Of Vasoconstriction
Regulation Of Cardiac Muscle Contraction
Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway
Neuron-glial Cell Signaling
Pathways
Acetylcholine regulates insulin secretion
Acetylcholine regulates insulin secretion
G alpha (q) signalling events
G alpha (q) signalling events
ADP signalling through P2Y purinoceptor 1
ADP signalling through P2Y purinoceptor 1
Thromboxane signalling through TP receptor
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
Thrombin signalling through proteinase activated receptors (PARs)
Adrenoceptors
G alpha (q) signalling events
G alpha (12/13) signalling events
Drugs
Amphetamine
Midodrine
Ranolazine
Ziprasidone
Cabergoline
Ropinirole
Dapiprazole
Amitriptyline
Olanzapine
Alfuzosin
Clozapine
Norepinephrine
Mirtazapine
Phenylephrine
Loxapine
Prochlorperazine
Prazosin
Prazosin
Imipramine
Chlorpromazine
Chlorpromazine
Buspirone
Nortriptyline
Amoxapine
Clonidine
Doxazosin
Labetalol
Nicardipine
Verapamil
Epinephrine
Thioridazine
Phentolamine
Ergotamine
Tizanidine
Tamsulosin
Paroxetine
Methoxamine
Trimipramine
Risperidone
Modafinil
Fenoldopam
Dobutamine
Quinidine
Phenoxybenzamine
Maprotiline
Oxymetazoline
Ergoloid mesylate
Promethazine
Carvedilol
Carvedilol
Doxepin
Nefazodone
Desipramine
Terazosin
Escitalopram
Pergolide
Bromocriptine
Quetiapine
Aripiprazole
Paliperidone
Mephentermine
Methotrimeprazine
Dextroamphetamine
Dextroamphetamine
Phendimetrazine
Periciazine
Acepromazine
Thioproperazine
Dronedarone
R450
Epicept NP-1
Sertindole
Mianserin
Pizotifen
Silodosin
Ocaperidone
Droxidopa
Xylometazoline
Perospirone
Brexpiprazole
Dosulepin
Etoperidone
Lorpiprazole
Cirazoline
Synephrine
Arotinolol
Moxisylyte
Aranidipine
Pipamperone
Racepinephrine
Dihydroergocornine
DL-Methylephedrine
Indigotindisulfonic acid
Tiapride
Dihydroergocristine
Aripiprazole lauroxil
Diseases
GWAS
Bipolar disorder (
31043756
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Diastolic blood pressure (
27841878
)
Plasma anti-thyroglobulin levels (
29678681
)
Psoriatic arthritis (
26626624
)
Pulse pressure (
27841878
)
Systolic blood pressure (
27841878
)
Interacting Genes
48 interacting genes:
ADHFE1
ADRA1B
AIP
AKAP13
BDKRB1
BTK
CCR5
CHRM3
CRHR1
CYTH1
CYTH2
FFAR1
FFAR2
GALR2
GRK2
GRM2
GRM4
GRM7
HTR2A
HTR2B
HTR2C
HTR6
KDR
LUM
MRGPRX1
NT5C3A
PIK3CA
PLCB1
PLCB2
PPT1
PTGIR
RGS13
RGS16
RGS18
RGS2
RGS4
RGS5
RGS7
RIC8A
RIC8B
S1PR2
S1PR3
SLC9A3R1
TBXA2R
TSHR
TTC1
TUB
VIPR1
11 interacting genes:
ADRA1A
AP2M1
EZR
FLNC
GNA11
GNAQ
NOS1
PPP1R9B
PRKCA
SAG
STAT1
Entrez ID
2776
147
HPRD ID
02998
00080
Ensembl ID
ENSG00000156052
ENSG00000170214
Uniprot IDs
A0A024R240
P50148
P35368
PDB IDs
6VU5
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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