GNA15 and LTB4R

Data Source:
HPRD (in vitro, in vivo)

		GNA15	LTB4R
Description		G protein subunit alpha 15	leukotriene B4 receptor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Heterotrimeric G-protein Complex Plasma Membrane Synapse	Plasma Membrane Integral Component Of Plasma Membrane Membrane Raft
	Molecular Function	G Protein-coupled Receptor Binding GTPase Activity GTP Binding G-protein Beta/gamma-subunit Complex Binding Type 2A Serotonin Receptor Binding Metal Ion Binding	Nucleotide Binding Leukotriene B4 Receptor Activity Leukotriene Receptor Activity G Protein-coupled Peptide Receptor Activity
	Biological Process	Action Potential G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Activation Of Phospholipase C Activity Phospholipase C-activating G Protein-coupled Acetylcholine Receptor Signaling Pathway Platelet Activation Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Phospholipase C-activating Dopamine Receptor Signaling Pathway	Muscle Contraction Inflammatory Response Immune Response G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Leukotriene Signaling Pathway
Pathways		Acetylcholine regulates insulin secretion Acetylcholine regulates insulin secretion G alpha (q) signalling events G alpha (q) signalling events ADP signalling through P2Y purinoceptor 1 ADP signalling through P2Y purinoceptor 1 Thromboxane signalling through TP receptor Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion Thrombin signalling through proteinase activated receptors (PARs)	Leukotriene receptors G alpha (q) signalling events
Drugs			Amelubant Morniflumate Leukotriene B4
Diseases
GWAS		Asthma ( 31959851 32296059) Clozapine-induced myocarditis in schizophrenia ( 32066683) Glucose homeostasis traits ( 25524916) Heart failure ( 20445134) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil count ( 32888494) White blood cell count ( 32888494)	Parent of origin effect on language impairment (paternal) ( 24571439)
Interacting Genes		19 interacting genes: ADRB2 APP CHRM2 CNR1 CNR2 CXCR1 CXCR2 F2R GRK2 GRM2 GRM4 HRH4 LTB4R OPRD1 OPRK1 OPRM1 PRKCA RGS2 TTC1	4 interacting genes: GNA15 GNAI2 GRK6 YWHAG
Entrez ID		2769	1241
HPRD ID		00760	03320
Ensembl ID		ENSG00000060558	ENSG00000213903
Uniprot IDs		P30679	Q15722
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?