LTB4R and GRK6

Data Source:
HPRD (in vitro)

		LTB4R	GRK6
Description		leukotriene B4 receptor	G protein-coupled receptor kinase 6
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane Raft	Plasma Membrane Membrane
	Molecular Function	Nucleotide Binding Leukotriene B4 Receptor Activity Leukotriene Receptor Activity G Protein-coupled Peptide Receptor Activity	G Protein-coupled Receptor Kinase Activity Protein Binding ATP Binding Beta-adrenergic Receptor Kinase Activity
	Biological Process	Muscle Contraction Inflammatory Response Immune Response G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Leukotriene Signaling Pathway	Protein Phosphorylation G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Wnt Signaling Pathway
Pathways		Leukotriene receptors G alpha (q) signalling events	G alpha (s) signalling events
Drugs		Amelubant Morniflumate Leukotriene B4
Diseases
GWAS		Parent of origin effect on language impairment (paternal) ( 24571439)	Activated partial thromboplastin time ( 22703881) Blood protein levels ( 28240269) Cardiac troponin-I levels ( 31014085) Chronic kidney disease ( 20383146) Extremely high intelligence ( 29520040) Glycine levels ( 30837465) Intelligence (MTAG) ( 29326435) Metabolite levels ( 22916037) Neutrophil percentage of white cells ( 32888494) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		4 interacting genes: GNA15 GNAI2 GRK6 YWHAG	19 interacting genes: ADRB2 BDKRB2 CHRM3 EDNRA EDNRB FBXO7 FSHR GIT1 ITGA5 KCNIP3 LTB4R PRSS23 RCVRN RHO SLC9A3R1 SNCA SNCB SNCG TBXA2R
Entrez ID		1241	2870
HPRD ID		03320	02925
Ensembl ID		ENSG00000213903	ENSG00000198055
Uniprot IDs		Q15722	B3KPS5 P43250
PDB IDs			2ACX 3NYN 3NYO
Enriched GO Terms of Interacting Partners?
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