LSM3 and LSM10

Data Source:
HPRD (two hybrid)

		LSM3	LSM10
Description		LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated	LSM10, U7 small nuclear RNA associated
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GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm U6 SnRNP Cytosol U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome Lsm2-8 Complex Lsm1-7-Pat1 Complex	Nucleoplasm U7 SnRNP Cajal Body Nuclear Body
	Molecular Function	RNA Binding Protein Binding U6 SnRNA 3'-end Binding	Protein Binding Histone Pre-mRNA DCP Binding U7 SnRNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing P-body Assembly Exonucleolytic Catabolism Of Deadenylated MRNA	Termination Of RNA Polymerase II Transcription MRNA Processing Histone MRNA Metabolic Process RNA Splicing Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway	SLBP independent Processing of Histone Pre-mRNAs RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
Drugs
Diseases
GWAS		Chronotype ( 30696823) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Height ( 31562340) Offspring birth weight ( 31043758) PR interval ( 32439900) Red blood cell count ( 32888494)	Diverticulitis ( 28585551) Neutrophil count ( 29403010)
Interacting Genes		48 interacting genes: CCND3 CDKN2D CEP95 CLNS1A CNOT7 DDIT4L DLX4 EEF1A1 EIF4EBP2 EXOSC1 EXOSC5 GDF9 GSTA1 HSPB1 INCA1 KEAP1 KLF3 LSM1 LSM10 LSM12 LSM2 LSM5 LSM6 LSM7 LSM8 NACC1 PIAS1 QKI SF3B2 SH3GLB2 SMN1 SNRPD1 SNRPD3 SNRPE SNRPF SNRPG TCL1A TEPSIN TFIP11 THOC5 TRAPPC2 TRAPPC2B UTP14A WDR77 WDR83 XPC XRN2 YBX1	10 interacting genes: BMPR2 CLNS1A LSM11 LSM3 MIR10B MIR128-1 MIR20A MIRLET7A1 SLBP SMN1
Entrez ID		27258	84967
HPRD ID		06283	14326
Ensembl ID		ENSG00000170860	ENSG00000181817
Uniprot IDs		P62310	Q969L4
PDB IDs		3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9	6V4X
Enriched GO Terms of Interacting Partners?
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