LSM3 and GSTA1

Data Source:
BioGRID (two hybrid)

		LSM3	GSTA1
Description		LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated	glutathione S-transferase alpha 1
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GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm U6 SnRNP Cytosol U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome Lsm2-8 Complex Lsm1-7-Pat1 Complex	Cytosol Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding U6 SnRNA 3'-end Binding	Glutathione Transferase Activity Glutathione Peroxidase Activity Steroid Delta-isomerase Activity Fatty Acid Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing P-body Assembly Exonucleolytic Catabolism Of Deadenylated MRNA	Prostaglandin Metabolic Process Glutathione Metabolic Process Xenobiotic Metabolic Process Epithelial Cell Differentiation Linoleic Acid Metabolic Process Cellular Oxidant Detoxification Glutathione Derivative Biosynthetic Process
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway	Glutathione conjugation Heme degradation
Drugs			Glutathione S-Hydroxycysteine 2-Hydroxyethyl Disulfide N-(4-Aminobutanoyl)-S-(4-methoxybenzyl)-L-cysteinylglycine Glutathione sulfonic acid Glutathione disulfide S-benzylglutathione S-Hexylglutathione Hypericin
Diseases
GWAS		Chronotype ( 30696823) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Height ( 31562340) Offspring birth weight ( 31043758) PR interval ( 32439900) Red blood cell count ( 32888494)	Blood protein levels ( 29875488) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494 27863252)
Interacting Genes		48 interacting genes: CCND3 CDKN2D CEP95 CLNS1A CNOT7 DDIT4L DLX4 EEF1A1 EIF4EBP2 EXOSC1 EXOSC5 GDF9 GSTA1 HSPB1 INCA1 KEAP1 KLF3 LSM1 LSM10 LSM12 LSM2 LSM5 LSM6 LSM7 LSM8 NACC1 PIAS1 QKI SF3B2 SH3GLB2 SMN1 SNRPD1 SNRPD3 SNRPE SNRPF SNRPG TCL1A TEPSIN TFIP11 THOC5 TRAPPC2 TRAPPC2B UTP14A WDR77 WDR83 XPC XRN2 YBX1	7 interacting genes: APP GSTA2 LSM3 PPP2CB RPAIN ST3GAL1 YWHAE
Entrez ID		27258	2938
HPRD ID		06283	00708
Ensembl ID		ENSG00000170860	ENSG00000243955
Uniprot IDs		P62310	A0A140VJK4 B7Z1F9 P08263
PDB IDs		3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9	1GSD 1GSE 1GSF 1GUH 1K3L 1K3O 1K3Y 1LBK 1PKW 1PKZ 1PL1 1PL2 1USB 1XWG 1YDK 2R3X 2R6K 3I69 3I6A 3IK9 3KTL 3L0H 3Q74 3U6V 3ZFB 3ZFL 4HJ2 5JCU 5LCZ 5LD0 6ATO 6ATP 6ATQ 6ATR 6YAW
Enriched GO Terms of Interacting Partners?
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