AGR3 and LYPD3

Data Source:
HPRD (two hybrid)

		AGR3	LYPD3
Description		anterior gradient 3, protein disulphide isomerase family member	LY6/PLAUR domain containing 3
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GO Annotations	Cellular Component	Endoplasmic Reticulum Intracellular Membrane-bounded Organelle	Extracellular Region Extracellular Space Plasma Membrane Integral Component Of Membrane Anchored Component Of Plasma Membrane
	Molecular Function	Dystroglycan Binding Protein Binding	Laminin Binding
	Biological Process	Biological_process Negative Regulation Of Cell Death	Cell-matrix Adhesion
Pathways			Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Coffee consumption ( 31959922 29367735) Cutaneous malignant melanoma ( 32341527 26237428) Cutaneous squamous cell carcinoma ( 32041948) Diffusing capacity of carbon monoxide ( 30694715) Lung cancer in ever smokers ( 28604730) Melanoma ( 28212542) Refractive error ( 32231278) Residual cognition ( 28441426) Rosacea symptom severity ( 29771307) Type 2 diabetes (dietary heme iron intake interaction) ( 23386860) Urinary albumin excretion ( 30220432) Urinary albumin excretion (no hypertensive medication) ( 30220432)	Cotinine glucuronidation ( 25293881)
Interacting Genes		35 interacting genes: AKT1 AP1B1 APC ASB10 BCAR3 CASP8 CATSPER1 CD46 CGRRF1 CNNM3 DAG1 DESI1 EDA2R ERLIN1 ESR2 FXYD3 KRTAP11-1 LIME1 LSM1 LYPD3 MMGT1 NRM NTAQ1 NUP62 PDZK1IP1 PRAF2 PTPN1 SGTA SGTB SPINT1 TGFB1 TIMMDC1 TMEM14B UBQLN1 UBQLN2	17 interacting genes: AGR2 AGR3 AURKA BAG4 BRMS1 CASP8 CHEK2 CTRB1 ERBB2 IGF1R LSP1 PALB2 PPM1D PTPRJ RB1CC1 SMAD4 STK11
Entrez ID		155465	27076
HPRD ID		16545	10783
Ensembl ID		ENSG00000173467	ENSG00000124466
Uniprot IDs		Q8TD06	B2RBR3 O95274
PDB IDs		3PH9	6IOM 6ION
Enriched GO Terms of Interacting Partners?
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