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PABPC1 and LINC01554
Data Source:
BioGRID
(unspecified method)
PABPC1
LINC01554
Description
poly(A) binding protein cytoplasmic 1
long intergenic non-protein coding RNA 1554
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Focal Adhesion
Cytoplasmic Stress Granule
Membrane
Lamellipodium
Cell Leading Edge
Cytoplasmic Ribonucleoprotein Granule
Extracellular Exosome
Catalytic Step 2 Spliceosome
Ribonucleoprotein Complex
Molecular Function
RNA Binding
MRNA 3'-UTR Binding
Protein Binding
Protein C-terminus Binding
Poly(A) Binding
Poly(U) RNA Binding
Translation Activator Activity
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
MRNA Splicing, Via Spliceosome
MRNA Polyadenylation
Translational Initiation
Gene Silencing By RNA
Regulation Of MRNA Stability
Positive Regulation Of Viral Genome Replication
Positive Regulation Of Translation
MRNA Stabilization
Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening
Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Pathways
L13a-mediated translational silencing of Ceruloplasmin expression
Deadenylation of mRNA
AUF1 (hnRNP D0) binds and destabilizes mRNA
Translation initiation complex formation
Regulation of expression of SLITs and ROBOs
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Body mass index (
26426971
)
Gut microbiota (bacterial taxa, hurdle binary method) (
32572223
)
High light scatter reticulocyte count (
32888494
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Mean corpuscular hemoglobin (
32888494
)
Reticulocyte count (
32888494
)
Reticulocyte fraction of red cells (
32888494
)
Interacting Genes
45 interacting genes:
ANAPC5
APBB1
ATXN2
CARM1
CHAF1A
CNOT6
CNOT7
CSDE1
DUX4
EIF4B
EIF4G1
EIF4G3
ERBB2
GSPT1
GSPT2
HBB
HNRNPD
HNRNPK
IL7R
ITCH
LINC01554
MAPKAPK2
NDRG1
PAIP1
PAIP2
PAIP2B
PAN2
PAN3
PCBP1
PCBP2
PCSK7
PIN1
PRMT6
PXN
RACK1
RBM4
SREK1
STAU1
SYCP3
SYNCRIP
TERT
TOB1
U2AF1
WBP4
YWHAG
141 interacting genes:
AARS1
ACADVL
ACIN1
ACTB
ACTG1
ACTN1
ACTN3
ACTR3
ALDOA
ANXA2
ANXA5
ANXA6
APEX1
ARHGAP1
ASS1
ATAD3A
ATIC
ATP5F1A
BZW2
CANX
CCT2
CCT3
CCT4
CCT6A
CCT7
CKAP4
CS
CTPS1
DDX3X
DDX46
DHX9
DNAH2
DNAJA1
DST
DYNC1H1
EDARADD
EEF1G
EEF2
EIF3A
EIF3E
EIF4A2
EIF4B
ENO1
ENO3
EPRS1
ERO1A
G3BP1
G6PD
GANAB
GAPDH
GARS1
GDI2
GPI
GTF2I
HIVEP2
HMCN1
HNRNPF
HSP90AA1
HSP90B1
HSPA1L
HSPA5
HSPA8
HSPA9
HSPD1
HYOU1
IDH1
IPO4
IPO7
IPO9
ITPR2
KARS1
KPNA1
KPNB1
KRT18
KRT7
KRT8
KRT8P3
LRPPRC
MCM7
MSN
MYO18A
NAP1L1
NAP1L4
NCBP1
NCL
NPM1
OLA1
OXCT1
PABPC1
PCBP2
PDIA3
PDIA6
PFAS
PGD
PGK1
PGM1
PHGDH
PKM
PLOD2
PMPCA
POR
PPP2R1A
PSMC1
PSMD2
PSMD7
PTBP1
RDX
RPL6
RPSA
RTCB
RTN4
SARS1
SEPTIN7
SEPTIN9
SERPINH1
SFPQ
SQSTM1
TARS1
TGFBI
THOP1
TKT
TTF2
TUBA1A
TUBA8
TUBB
TUBB2A
TUBB3
TUBB4A
TUBB4B
TUBB6
TUFM
TXNRD1
TYMP
UBA1
VCL
VCP
VIM
VPS35
WARS1
XPO1
XRCC5
Entrez ID
26986
202299
HPRD ID
05247
16896
Ensembl ID
ENSG00000070756
ENSG00000236882
Uniprot IDs
A0A024R9C1
P11940
PDB IDs
1CVJ
1G9L
1JGN
1JH4
2K8G
2RQG
2RQH
2X04
3KTP
3KTR
3KUI
3KUJ
3KUR
3KUS
3KUT
3PKN
3PTH
4F02
4F25
4F26
5DX1
5DX8
5DXA
5LGP
5LGQ
5LGR
5LGS
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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