LINC01554 and XPO1

Data Source:
BioGRID (unspecified method)

		LINC01554	XPO1
Description		long intergenic non-protein coding RNA 1554	exportin 1
Image		No pdb structure
GO Annotations	Cellular Component		Kinetochore Nucleus Nuclear Envelope Annulate Lamellae Nucleoplasm Nucleolus Cytoplasm Cytosol Cajal Body Membrane Nuclear Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle Host Cell Ribonucleoprotein Complex
	Molecular Function		RNA Binding Nuclear Export Signal Receptor Activity Protein Binding
	Biological Process		Ribosomal Subunit Export From Nucleus Ribosomal Large Subunit Export From Nucleus Ribosomal Small Subunit Export From Nucleus Protein Export From Nucleus Nucleocytoplasmic Transport Viral Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Ribosome Biogenesis Regulation Of MRNA Stability MRNA Transport Intracellular Transport Of Virus
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Rev-mediated nuclear export of HIV RNA NEP/NS2 Interacts with the Cellular Export Machinery Downregulation of TGF-beta receptor signaling Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Deactivation of the beta-catenin transactivating complex HuR (ELAVL1) binds and stabilizes mRNA RHO GTPases Activate Formins MAPK6/MAPK4 signaling Mitotic Prometaphase Cyclin A/B1/B2 associated events during G2/M transition Estrogen-dependent nuclear events downstream of ESR-membrane signaling EML4 and NUDC in mitotic spindle formation
Drugs			Selinexor
Diseases
GWAS			Atrial fibrillation ( 29892015) Eosinophil counts ( 32888494 27863252) Erectile dysfunction ( 30583798) Mean reticulocyte volume ( 32888494) Neutrophil count ( 32888494) Sum eosinophil basophil counts ( 27863252) Systemic lupus erythematosus ( 28714469) Urinary sodium excretion ( 31409800) White blood cell count ( 32888494)
Interacting Genes		141 interacting genes: AARS1 ACADVL ACIN1 ACTB ACTG1 ACTN1 ACTN3 ACTR3 ALDOA ANXA2 ANXA5 ANXA6 APEX1 ARHGAP1 ASS1 ATAD3A ATIC ATP5F1A BZW2 CANX CCT2 CCT3 CCT4 CCT6A CCT7 CKAP4 CS CTPS1 DDX3X DDX46 DHX9 DNAH2 DNAJA1 DST DYNC1H1 EDARADD EEF1G EEF2 EIF3A EIF3E EIF4A2 EIF4B ENO1 ENO3 EPRS1 ERO1A G3BP1 G6PD GANAB GAPDH GARS1 GDI2 GPI GTF2I HIVEP2 HMCN1 HNRNPF HSP90AA1 HSP90B1 HSPA1L HSPA5 HSPA8 HSPA9 HSPD1 HYOU1 IDH1 IPO4 IPO7 IPO9 ITPR2 KARS1 KPNA1 KPNB1 KRT18 KRT7 KRT8 KRT8P3 LRPPRC MCM7 MSN MYO18A NAP1L1 NAP1L4 NCBP1 NCL NPM1 OLA1 OXCT1 PABPC1 PCBP2 PDIA3 PDIA6 PFAS PGD PGK1 PGM1 PHGDH PKM PLOD2 PMPCA POR PPP2R1A PSMC1 PSMD2 PSMD7 PTBP1 RDX RPL6 RPSA RTCB RTN4 SARS1 SEPTIN7 SEPTIN9 SERPINH1 SFPQ SQSTM1 TARS1 TGFBI THOP1 TKT TTF2 TUBA1A TUBA8 TUBB TUBB2A TUBB3 TUBB4A TUBB4B TUBB6 TUFM TXNRD1 TYMP UBA1 VCL VCP VIM VPS35 WARS1 XPO1 XRCC5	80 interacting genes: ABL1 ADAR AGFG1 AHR ANP32A ANP32B APC ATF2 BECN1 BIRC5 BRCA2 CCND1 CDC25A CDC42 CDCA4 CDKN1B CHEK1 CHORDC1 CIITA CRK DDX3X DESI1 DR1 E2F4 E2F5 EIF5A ERF FBXO7 FOXO4 HDAC3 HNF4A HSPA9 HSPB1 IRF5 KIF17 LINC01554 MAPK6 NF2 NMD3 NPM1 NUCB1 NUCB2 NUP153 NUP214 NUP50 NUP62 NXF3 NXT1 ORC1 PHAX PHB PKIA RAD51 RAN RANBP2 RANBP3 RCC1 RCN2 RGS14 RIC8A RPS6KB1 SERPINB1 SERTAD2 SIRT2 SMAD1 SMARCB1 SMURF1 SMURF2 SNUPN SOX2 STAT1 STRADA SUMO1 SUMO2 TERF2IP TERT TOP2A TOP2B TP53 TP73
Entrez ID		202299	7514
HPRD ID		16896	03975
Ensembl ID		ENSG00000236882	ENSG00000082898
Uniprot IDs			B3KWD0 O14980
PDB IDs			1W9C 2L1L 3GB8 4BSM 4BSN 5DIS 6TVO
Enriched GO Terms of Interacting Partners?
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