SEC22A and CYBRD1

Data Source:
BioGRID (two hybrid)

		SEC22A	CYBRD1
Description		SEC22 homolog A, vesicle trafficking protein	cytochrome b reductase 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Lysosomal Membrane Plasma Membrane Integral Component Of Membrane Brush Border Membrane Extracellular Exosome
	Molecular Function	Transporter Activity Protein Binding	Ferric-chelate Reductase Activity Protein Binding Oxidoreductase Activity Metal Ion Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport	Cellular Iron Ion Homeostasis Response To Iron Ion
Pathways		COPII-mediated vesicle transport	Iron uptake and transport
Drugs
Diseases
GWAS		Gestational age at birth (maternal effect) ( 28877031)	Body fat distribution (arm fat ratio) ( 30664634) Heel bone mineral density ( 30598549) Pulse pressure ( 30224653)
Interacting Genes		106 interacting genes: ADGRG3 AQP6 ASGR2 ATP6AP2 BIK BNIP3 C10orf67 C16orf54 C16orf92 CALN1 CD207 CD300A CD7 CD74 CISD2 CLEC10A CLEC12B CLEC2D CLEC7A CREB3L1 CYB561 CYBRD1 DDIT4L DIABLO DTX2 EDA ELOVL4 ERLIN1 ERVFRD-1 FAM174A FAM209A FATE1 FUT3 GAD2 GGT6 GJB5 GJB6 GPR37L1 GRAMD2B HAVCR2 HCST HSD17B11 ICAM3 KCNJ2 LDLRAD1 LHFPL5 LMNA LPAR6 LRRC25 LSMEM2 MCOLN1 MFF MGST2 MINAR1 MS4A14 MS4A3 MS4A4A MSR1 OPRM1 PACC1 PEX12 PHB PTGES RASGRP4 RETREG3 RILPL1 RNASEK RNF144A RNF19B RNF5 SAR1A SCN3B SDHAF2 SFTPC SLC14A2 SLC30A2 SLC35C2 SLC39A2 SMIM3 SPAG4 STMN4 STOML3 STX1A STX2 STX4 SUSD3 SYNE4 TFR2 TLCD4 TMED9 TMEM106C TMEM159 TMEM174 TMEM237 TMEM45B TMEM52B TMEM71 TMEM79 TMIE TMPRSS2 TNFSF14 TP53INP1 TRAT1 TRIM59 TYRP1 ZFYVE27	20 interacting genes: CREB3 FKBP8 GIMAP5 GOSR2 HMOX1 LMNA LPAR3 NEDD4L PLP2 RABAC1 SEC22A SERP1 SERP2 STX4 STX7 TMEM120A TMEM65 VAPA VAPB ZFPL1
Entrez ID		26984	79901
HPRD ID		15313	05764
Ensembl ID		ENSG00000121542	ENSG00000071967
Uniprot IDs		Q96IW7	Q53TN4
PDB IDs			5ZLE 5ZLG
Enriched GO Terms of Interacting Partners?
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