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SEC22A and DIABLO
Data Source:
BioGRID
(two hybrid)
SEC22A
DIABLO
Description
SEC22 homolog A, vesicle trafficking protein
diablo IAP-binding mitochondrial protein
Image
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
Mitochondrion
Mitochondrial Intermembrane Space
Cytosol
Cytoplasmic Side Of Plasma Membrane
CD40 Receptor Complex
Molecular Function
Transporter Activity
Protein Binding
Protein Binding
Biological Process
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Protein Transport
Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C
Positive Regulation Of Apoptotic Process
Neuron Apoptotic Process
Intrinsic Apoptotic Signaling Pathway
Pathways
COPII-mediated vesicle transport
Release of apoptotic factors from the mitochondria
SMAC (DIABLO) binds to IAPs
SMAC (DIABLO) binds to IAPs
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
SMAC, XIAP-regulated apoptotic response
Regulation of the apoptosome activity
Drugs
Phenethyl Isothiocyanate
Diseases
GWAS
Gestational age at birth (maternal effect) (
28877031
)
Interacting Genes
106 interacting genes:
ADGRG3
AQP6
ASGR2
ATP6AP2
BIK
BNIP3
C10orf67
C16orf54
C16orf92
CALN1
CD207
CD300A
CD7
CD74
CISD2
CLEC10A
CLEC12B
CLEC2D
CLEC7A
CREB3L1
CYB561
CYBRD1
DDIT4L
DIABLO
DTX2
EDA
ELOVL4
ERLIN1
ERVFRD-1
FAM174A
FAM209A
FATE1
FUT3
GAD2
GGT6
GJB5
GJB6
GPR37L1
GRAMD2B
HAVCR2
HCST
HSD17B11
ICAM3
KCNJ2
LDLRAD1
LHFPL5
LMNA
LPAR6
LRRC25
LSMEM2
MCOLN1
MFF
MGST2
MINAR1
MS4A14
MS4A3
MS4A4A
MSR1
OPRM1
PACC1
PEX12
PHB
PTGES
RASGRP4
RETREG3
RILPL1
RNASEK
RNF144A
RNF19B
RNF5
SAR1A
SCN3B
SDHAF2
SFTPC
SLC14A2
SLC30A2
SLC35C2
SLC39A2
SMIM3
SPAG4
STMN4
STOML3
STX1A
STX2
STX4
SUSD3
SYNE4
TFR2
TLCD4
TMED9
TMEM106C
TMEM159
TMEM174
TMEM237
TMEM45B
TMEM52B
TMEM71
TMEM79
TMIE
TMPRSS2
TNFSF14
TP53INP1
TRAT1
TRIM59
TYRP1
ZFYVE27
42 interacting genes:
AGTRAP
APOC2
APOC4
AREL1
ARL6IP1
ARNT
BEX3
BIRC2
BIRC3
BIRC5
BIRC6
BIRC7
CASP9
CMTM4
DERL2
DGAT2L6
DHRS1
E2F1
EEF1A1
FADS6
FKBP7
HSD17B13
HTRA2
LTBR
MAML2
MICOS13
MPC2
NR4A1
RHBDD2
RMDN2
SEC22A
SFT2D1
SLC17A9
SLC25A47
SLC66A2
STMN4
SYP
TIMMDC1
UBE2K
UFM1
XIAP
ZNF746
Entrez ID
26984
56616
HPRD ID
15313
05560
Ensembl ID
ENSG00000121542
ENSG00000184047
Uniprot IDs
Q96IW7
A0A024RBT2
A0A0S2Z5P6
A0A0S2Z5U7
K7X1S0
Q502X2
Q9NR28
PDB IDs
1FEW
1G3F
1G73
1OXQ
1TW6
1XB0
1XB1
3D9U
3UIH
3UIJ
4TX5
6JX6
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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