SEC22A and CD300A

Data Source:
BioGRID (two hybrid)

		SEC22A	CD300A
Description		SEC22 homolog A, vesicle trafficking protein	CD300a molecule
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Plasma Membrane Membrane Integral Component Of Membrane Extracellular Exosome Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Transporter Activity Protein Binding	Phosphatidylserine Binding Transmembrane Signaling Receptor Activity Protein Binding Phosphatidylethanolamine Binding Signaling Receptor Activity
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport	Cell Adhesion Negative Regulation Of B Cell Proliferation Positive Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Mast Cell Activation Involved In Immune Response Negative Regulation Of MyD88-dependent Toll-like Receptor Signaling Pathway Negative Regulation Of Mast Cell Degranulation Neutrophil Degranulation Negative Regulation Of MAP Kinase Activity Negative Regulation Of Fibroblast Proliferation Regulation Of Immune Response Regulation Of T Cell Receptor Signaling Pathway Negative Regulation Of B Cell Receptor Signaling Pathway Negative Regulation Of NK T Cell Activation Negative Regulation Of Phagocytosis, Engulfment Negative Regulation Of Neutrophil Activation Negative Regulation Of Eosinophil Activation Negative Regulation Of Activation Of Janus Kinase Activity Negative Regulation Of Eosinophil Migration
Pathways		COPII-mediated vesicle transport	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Neutrophil degranulation
Drugs
Diseases
GWAS		Gestational age at birth (maternal effect) ( 28877031)	Blood protein levels ( 30072576 29875488) Neurological blood protein biomarker levels ( 31320639)
Interacting Genes		106 interacting genes: ADGRG3 AQP6 ASGR2 ATP6AP2 BIK BNIP3 C10orf67 C16orf54 C16orf92 CALN1 CD207 CD300A CD7 CD74 CISD2 CLEC10A CLEC12B CLEC2D CLEC7A CREB3L1 CYB561 CYBRD1 DDIT4L DIABLO DTX2 EDA ELOVL4 ERLIN1 ERVFRD-1 FAM174A FAM209A FATE1 FUT3 GAD2 GGT6 GJB5 GJB6 GPR37L1 GRAMD2B HAVCR2 HCST HSD17B11 ICAM3 KCNJ2 LDLRAD1 LHFPL5 LMNA LPAR6 LRRC25 LSMEM2 MCOLN1 MFF MGST2 MINAR1 MS4A14 MS4A3 MS4A4A MSR1 OPRM1 PACC1 PEX12 PHB PTGES RASGRP4 RETREG3 RILPL1 RNASEK RNF144A RNF19B RNF5 SAR1A SCN3B SDHAF2 SFTPC SLC14A2 SLC30A2 SLC35C2 SLC39A2 SMIM3 SPAG4 STMN4 STOML3 STX1A STX2 STX4 SUSD3 SYNE4 TFR2 TLCD4 TMED9 TMEM106C TMEM159 TMEM174 TMEM237 TMEM45B TMEM52B TMEM71 TMEM79 TMIE TMPRSS2 TNFSF14 TP53INP1 TRAT1 TRIM59 TYRP1 ZFYVE27	6 interacting genes: KRT38 KRTAP10-3 SEC22A TMEM199 TMEM218 TMEM60
Entrez ID		26984	11314
HPRD ID		15313	09492
Ensembl ID		ENSG00000121542	ENSG00000167851
Uniprot IDs		Q96IW7	J3QKQ4 Q9UGN4
PDB IDs			2Q87
Enriched GO Terms of Interacting Partners?
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