Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
SEC22A and STX4
Data Source:
BioGRID
(two hybrid, two hybrid)
SEC22A
STX4
Description
SEC22 homolog A, vesicle trafficking protein
syntaxin 4
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
Storage Vacuole
Extracellular Space
Endosome
Vacuole
Trans-Golgi Network
Cytosol
Plasma Membrane
Synaptic Vesicle
Cell Surface
Endomembrane System
Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Lamellipodium
Phagocytic Vesicle Membrane
SNARE Complex
Myelin Sheath Adaxonal Region
Somatodendritic Compartment
Specific Granule
Dendritic Spine
Lateral Loop
Synapse
Perinuclear Region Of Cytoplasm
Presynaptic Active Zone Membrane
Extracellular Exosome
Postsynapse
Glutamatergic Synapse
Molecular Function
Transporter Activity
Protein Binding
SNARE Binding
SNAP Receptor Activity
Protein Binding
Sphingomyelin Phosphodiesterase Activator Activity
Biological Process
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Protein Transport
Positive Regulation Of Immunoglobulin Production
Intracellular Protein Transport
Exocytosis
Post-Golgi Vesicle-mediated Transport
Vesicle Fusion
Positive Regulation Of Cell Population Proliferation
Regulation Of Exocytosis
Cytokine-mediated Signaling Pathway
Positive Regulation Of Cell Migration
Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Cellular Response To Oxidative Stress
SNARE Complex Assembly
Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Positive Regulation Of Catalytic Activity
Positive Regulation Of Eosinophil Degranulation
Positive Regulation Of Cell Adhesion
Vesicle Docking
Organelle Fusion
Positive Regulation Of Chemotaxis
Long-term Synaptic Potentiation
Cellular Response To Interferon-gamma
Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Positive Regulation Of Protein Localization To Plasma Membrane
Cornified Envelope Assembly
Vesicle Fusion With Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Membrane
Positive Regulation Of Protein Localization To Cell Surface
Pathways
COPII-mediated vesicle transport
Disinhibition of SNARE formation
ER-Phagosome pathway
Translocation of SLC2A4 (GLUT4) to the plasma membrane
trans-Golgi Network Vesicle Budding
Other interleukin signaling
Drugs
Diseases
GWAS
Gestational age at birth (maternal effect) (
28877031
)
Response to metformin (IC50) (
28173075
)
Triglyceride levels (
32203549
)
Interacting Genes
106 interacting genes:
ADGRG3
AQP6
ASGR2
ATP6AP2
BIK
BNIP3
C10orf67
C16orf54
C16orf92
CALN1
CD207
CD300A
CD7
CD74
CISD2
CLEC10A
CLEC12B
CLEC2D
CLEC7A
CREB3L1
CYB561
CYBRD1
DDIT4L
DIABLO
DTX2
EDA
ELOVL4
ERLIN1
ERVFRD-1
FAM174A
FAM209A
FATE1
FUT3
GAD2
GGT6
GJB5
GJB6
GPR37L1
GRAMD2B
HAVCR2
HCST
HSD17B11
ICAM3
KCNJ2
LDLRAD1
LHFPL5
LMNA
LPAR6
LRRC25
LSMEM2
MCOLN1
MFF
MGST2
MINAR1
MS4A14
MS4A3
MS4A4A
MSR1
OPRM1
PACC1
PEX12
PHB
PTGES
RASGRP4
RETREG3
RILPL1
RNASEK
RNF144A
RNF19B
RNF5
SAR1A
SCN3B
SDHAF2
SFTPC
SLC14A2
SLC30A2
SLC35C2
SLC39A2
SMIM3
SPAG4
STMN4
STOML3
STX1A
STX2
STX4
SUSD3
SYNE4
TFR2
TLCD4
TMED9
TMEM106C
TMEM159
TMEM174
TMEM237
TMEM45B
TMEM52B
TMEM71
TMEM79
TMIE
TMPRSS2
TNFSF14
TP53INP1
TRAT1
TRIM59
TYRP1
ZFYVE27
72 interacting genes:
ABI2
ACTB
ANKRD46
BET1
CYBRD1
DLG1
DNAJC5
EMD
FAXDC2
GIMAP5
GOSR2
GPR152
ITSN2
LLGL1
LMNA
NAPA
NAPB
NSF
PLP1
PSMA3
RAB11A
RAB4A
RAB5A
RNF4
SCRIB
SEC22A
SEC22B
SEPTIN5
SERP1
SGPL1
SH3GLB2
SNAP23
SNAP25
SNAP29
SNAP47
STX10
STX11
STX12
STX16
STX1A
STX1B
STX2
STX3
STX5
STX6
STX7
STX8
STXBP3
STXBP4
STXBP5
STXBP6
SYT1
SYT4
SYT7
TCEANC
TMEM199
TMEM203
TRAF3IP3
TXLNA
TXLNB
TXLNG
USE1
VAMP1
VAMP2
VAMP3
VAMP4
VAMP5
VAMP7
VAMP8
VAPB
VTI1B
ZFPL1
Entrez ID
26984
6810
HPRD ID
15313
01722
Ensembl ID
ENSG00000121542
ENSG00000103496
Uniprot IDs
Q96IW7
B7Z425
Q12846
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?