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SPAG8 and CFP
Data Source:
BioGRID
(two hybrid)
SPAG8
CFP
Description
sperm associated antigen 8
complement factor properdin
Image
No pdb structure
GO Annotations
Cellular Component
Acrosomal Vesicle
Nucleus
Cytoplasm
Spindle
Membrane
Extracellular Region
Extracellular Space
Endoplasmic Reticulum Lumen
Specific Granule Lumen
Collagen-containing Extracellular Matrix
Tertiary Granule Lumen
Molecular Function
Molecular_function
Protein Binding
Microtubule Binding
Protein Binding
Biological Process
Cell Cycle
Spermatogenesis
Single Fertilization
Biological_process
Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Immune Response
Complement Activation
Complement Activation, Alternative Pathway
Regulation Of Complement Activation
Defense Response To Bacterium
Neutrophil Degranulation
Pathways
Alternative complement activation
Activation of C3 and C5
Defective B3GALTL causes Peters-plus syndrome (PpS)
O-glycosylation of TSR domain-containing proteins
Neutrophil degranulation
Regulation of Complement cascade
Drugs
Diseases
Alternative complement pathway component defects, including the following four diseases: Factor B deficiency; Factor D deficiency; Factor H deficiency; Properdin deficiency
GWAS
Blood protein levels (
28240269
)
Brain morphology (MOSTest) (
32665545
)
Interacting Genes
87 interacting genes:
ARMC5
B9D2
BATF2
C19orf54
CARM1
CCDC120
CCNC
CDC23
CFP
CSTF2
CSTF2T
CTAG1A
CTAG1B
DMRT3
DOK3
DTX2
DYNLL2
EGFL7
FAM168B
GIGYF1
GLYCTK
GPSM3
HR
INCA1
INTS11
JMJD4
KDM3B
KLHL32
KRT34
KRTAP10-8
KRTAP11-1
KRTAP13-3
KRTAP15-1
KRTAP19-2
KRTAP19-6
KRTAP19-7
KRTAP21-2
KRTAP26-1
KRTAP3-1
KRTAP6-2
KRTAP7-1
LASP1
MEOX1
METTL15
MGAT5B
NEDD4L
NHLRC4
NSD3
NUDT21
PATZ1
PEF1
PFDN5
PHF1
PITX1
PLA2G10
PRMT1
PRMT2
PRMT5
PRR35
RAN
RBP3
RIPK4
RNF125
RUSC1
SERGEF
SMUG1
SMYD1
SNRPB
SNRPC
SYNGAP1
TEKT3
TEKT5
TENT5B
TRIB3
TRIM42
TSC1
TTC23
UBAP2
UBQLN1
UBQLN4
USP2
VPS37C
YPEL3
ZBTB32
ZIC1
ZNF34
ZNF581
32 interacting genes:
BANF2
C3
CFAP206
CFB
CYSRT1
FHL5
FKBP6
GEMIN4
GNE
HEXIM2
HOXA1
KCTD9
KLHL38
KRTAP11-1
KRTAP12-2
KRTAP3-1
KRTAP6-2
LCE1A
LONRF1
MID2
MTOR
NEK6
NOXA1
PRKAB2
RECK
SMARCC1
SPAG8
STK16
TRIP13
VENTX
ZNF330
ZNF414
Entrez ID
26206
5199
HPRD ID
12039
02308
Ensembl ID
ENSG00000137098
ENSG00000126759
Uniprot IDs
A0A140VJV0
Q99932
A0A0S2Z4I5
P27918
PDB IDs
1W0R
1W0S
6RUR
6RUS
6RUV
6RV6
6S08
6S0A
6S0B
6SEJ
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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