SPAG8 and PATZ1

Data Source:
BioGRID (two hybrid)

		SPAG8	PATZ1
Description		sperm associated antigen 8	POZ/BTB and AT hook containing zinc finger 1
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Nucleus Cytoplasm Spindle Membrane	Nucleus Nucleoplasm
	Molecular Function	Molecular_function Protein Binding Microtubule Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Ubiquitin Protein Ligase Binding Metal Ion Binding
	Biological Process	Cell Cycle Spermatogenesis Single Fertilization Biological_process Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Spermatogenesis Male Gonad Development Negative Regulation Of Endothelial Cell Migration T Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Brain morphology (MOSTest) ( 32665545)	Eosinophil percentage of white cells ( 32888494) Fish- and plant-related diet ( 32066663) Height ( 31562340) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Red cell distribution width ( 28957414) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)
Interacting Genes		87 interacting genes: ARMC5 B9D2 BATF2 C19orf54 CARM1 CCDC120 CCNC CDC23 CFP CSTF2 CSTF2T CTAG1A CTAG1B DMRT3 DOK3 DTX2 DYNLL2 EGFL7 FAM168B GIGYF1 GLYCTK GPSM3 HR INCA1 INTS11 JMJD4 KDM3B KLHL32 KRT34 KRTAP10-8 KRTAP11-1 KRTAP13-3 KRTAP15-1 KRTAP19-2 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP26-1 KRTAP3-1 KRTAP6-2 KRTAP7-1 LASP1 MEOX1 METTL15 MGAT5B NEDD4L NHLRC4 NSD3 NUDT21 PATZ1 PEF1 PFDN5 PHF1 PITX1 PLA2G10 PRMT1 PRMT2 PRMT5 PRR35 RAN RBP3 RIPK4 RNF125 RUSC1 SERGEF SMUG1 SMYD1 SNRPB SNRPC SYNGAP1 TEKT3 TEKT5 TENT5B TRIB3 TRIM42 TSC1 TTC23 UBAP2 UBQLN1 UBQLN4 USP2 VPS37C YPEL3 ZBTB32 ZIC1 ZNF34 ZNF581	81 interacting genes: AKAP8L BACH1 BACH2 BOLL BPIFA1 C11orf1 C19orf54 CEP76 CLK1 CPSF7 CYSRT1 DAZAP2 DVL3 EYA2 FAM168A FAM168B GOLGA6L9 GPANK1 HNRNPF HNRNPH1 HSPB2 HSPB2-C11orf52 HYI IQUB KLF1 KLHDC7B KRT33B KRTAP12-2 KRTAP13-2 KRTAP15-1 KRTAP19-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP3-1 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 LMO2 LONRF1 LURAP1L LZTS2 MDFI MITF MSX2 NFKBID NHLRC4 OIP5 PFDN5 PHF1 PPP1R16B PPP1R37 PRDM14 PRDM6 PRKAR1A PRR20A PRR20B PRR20C PRR20D PRR20E PRR22 RBM10 RBPMS RBPMS2 RFX6 RIPPLY1 RNF4 SLAIN1 SMYD1 SPAG8 TLE5 TNS2 TRAF1 TRIP6 TSC1 WWOX WWP2 ZBTB32 ZIC1 ZIM2
Entrez ID		26206	23598
HPRD ID		12039	05522
Ensembl ID		ENSG00000137098	ENSG00000100105
Uniprot IDs		A0A140VJV0 Q99932	A0A024R1F8 A0A024R1H7 A0A024R1M5 Q9HBE1
PDB IDs			2EPP 2EPQ 2EPR 2EPS 2YT9
Enriched GO Terms of Interacting Partners?
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