TXN2 and LCN2

Data Source:
BioGRID (two hybrid)

		TXN2	LCN2
Description		thioredoxin 2	lipocalin 2
Image
GO Annotations	Cellular Component	Nucleolus Mitochondrion Mitochondrial Matrix Dendrite Neuronal Cell Body	Extracellular Region Extracellular Space Specific Granule Lumen Extracellular Exosome
	Molecular Function	Protein Binding Peptide-methionine (S)-S-oxide Reductase Activity Protein Disulfide Oxidoreductase Activity Peptide-methionine (R)-S-oxide Reductase Activity Protein-containing Complex Binding	Iron Ion Binding Protein Binding Small Molecule Binding Identical Protein Binding Enterobactin Binding
	Biological Process	Sulfur Amino Acid Catabolic Process Response To Hypoxia Glycerol Ether Metabolic Process Response To Oxidative Stress Response To Hormone Response To Glucose Response To Organic Cyclic Compound Cellular Response To Nutrient Levels Response To Drug Cell Redox Homeostasis Response To Axon Injury	Cellular Iron Ion Homeostasis Apoptotic Process Siderophore Transport Cytokine-mediated Signaling Pathway Antimicrobial Humoral Response Defense Response To Bacterium Neutrophil Degranulation Innate Immune Response Sequestering Of Iron Ion Positive Regulation Of Cold-induced Thermogenesis
Pathways		Degradation of cysteine and homocysteine Detoxification of Reactive Oxygen Species	Interleukin-4 and Interleukin-13 signaling Neutrophil degranulation Metal sequestration by antimicrobial proteins Iron uptake and transport Iron uptake and transport
Drugs			Methyl nonanoate 2,3-Dihydroxy-Benzoic Acid Carboxymycobactin S 2,3,-Dihydroxybenzoylserine Carboxymycobactin T Trencam-3,2-Hopo
Diseases
GWAS
Interacting Genes		79 interacting genes: ABI3 AGTRAP ALDOB ANKRD36B AP2B1 BCAS2 BHLHB9 C11orf49 CCDC197 CDCA4 CEP70 CGGBP1 CHMP1A CIB4 CRACR2B DCTD DDIT3 ETHE1 FAM9B FHL5 FMNL2 GOLGA6L9 GPRASP2 GTPBP2 GUCD1 HAUS1 HAUS8 KAZN KRT18 KRT27 KRT40 LCN2 MAGEA11 MAGEA4 MAGEB2 MAPRE2 MAPRE3 MDFI MEOX2 MIPOL1 MLH1 MRFAP1 MRFAP1L1 MTUS2 MYL9 NUTM1 ODAD1 PEX19 POMC PPCDC PPP1R16B PSME3 RABAC1 RABGEF1 RBM45 REEP6 RPIA SAT1 SCYL3 SHARPIN SPTA1 SSNA1 STN1 STUB1 SYCE1 TFIP11 THAP1 TIFA TMOD4 TRIM21 TRIP6 TTC32 UCHL5 UQCC2 VIM VPS52 ZBTB14 ZMYND12 ZSCAN32	61 interacting genes: ALDH7A1 ALKBH4 ASB10 ASPH BEX2 BMF C20orf85 CAMLG CCNC CDSN CHIC2 CLMP CTDSP2 EHHADH FAAP20 FAM25A FAM25C FAM25G HDDC2 HGF LAIR2 LNPEP LRP2 LY96 MAGED4B MMP2 MMP9 MSRB3 MYDGF NDUFB2 NEIL2 ODAPH P4HB PDIA4 PELI1 PICK1 PIN1 POLL POU4F2 PRKAA2 PTRH1 RAMP2 SCNM1 SEC61G SGTA SGTB TBC1D21 TRAPPC2L TRH TRIAP1 TRIM32 TSG101 TTC23 TXN2 UBASH3A UBE2F UBQLN1 UBQLN2 VEZF1 XRN2 ZBED1
Entrez ID		25828	3934
HPRD ID		07161	02551
Ensembl ID		ENSG00000100348	ENSG00000148346
Uniprot IDs		Q99757	P80188
PDB IDs		1UVZ 1W4V 1W89	1DFV 1L6M 1NGL 1QQS 1X71 1X89 1X8U 3BY0 3CBC 3CMP 3DSZ 3DTQ 3FW4 3FW5 3HWD 3HWE 3HWF 3HWG 3I0A 3K3L 3PEC 3PED 3T1D 3TF6 3TZS 3U0D 4GH7 4IAW 4IAX 4K19 4MVI 4MVK 4MVL 4QAE 4ZFX 4ZHC 4ZHD 4ZHF 4ZHG 4ZHH 5JR8 5KHP 5KIC 5KID 5MHH 5N47 5N48 5NKN 6GQZ 6GR0 6O5D 6QMU 6S8V 6SUA
Enriched GO Terms of Interacting Partners?
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